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Atomistry » Fluorine » PDB 3fls-3g70 » 3g3m » |
Fluorine in PDB 3g3m: Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-UmpEnzymatic activity of Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-Ump
All present enzymatic activity of Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-Ump:
4.1.1.23; Protein crystallography data
The structure of Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-Ump, PDB code: 3g3m
was solved by
Y.Liu,
H.L.Tang,
A.M.Bello,
E.Poduch,
L.P.Kotra,
E.F.Pai,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-Ump
(pdb code 3g3m). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-Ump, PDB code: 3g3m: Fluorine binding site 1 out of 1 in 3g3mGo back to Fluorine Binding Sites List in 3g3m
Fluorine binding site 1 out
of 1 in the Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Covalently Modified By 5-Fluoro-6-Iodo-Ump
Mono view Stereo pair view
Reference:
A.M.Bello,
D.Konforte,
E.Poduch,
C.Furlonger,
L.Wei,
Y.Liu,
M.Lewis,
E.F.Pai,
C.J.Paige,
L.P.Kotra.
Structure-Activity Relationships of Orotidine-5'-Monophosphate Decarboxylase Inhibitors As Anticancer Agents. J.Med.Chem. V. 52 1648 2009.
Page generated: Sun Dec 13 11:46:33 2020
ISSN: ISSN 0022-2623 PubMed: 19260677 DOI: 10.1021/JM801224T |
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