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Atomistry » Fluorine » PDB 3g72-3gwv » 3gp0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3g72-3gwv » 3gp0 » |
Fluorine in PDB 3gp0: Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with NilotinibEnzymatic activity of Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib
All present enzymatic activity of Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib:
2.7.11.24; Protein crystallography data
The structure of Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib, PDB code: 3gp0
was solved by
P.Filippakopoulos,
A.Barr,
O.Fedorov,
T.Keates,
M.Soundararajan,
J.Elkins,
E.Salah,
N.Burgess-Brown,
E.Ugochukwu,
A.C.W.Pike,
J.Muniz,
A.Roos,
A.Chaikuad,
F.Von Delft,
C.H.Arrowsmith,
A.M.Edwards,
J.Weigelt,
C.Bountra,
S.Knapp,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3gp0:
The structure of Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib
(pdb code 3gp0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib, PDB code: 3gp0: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 3gp0Go back to Fluorine Binding Sites List in 3gp0
Fluorine binding site 1 out
of 3 in the Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 3gp0Go back to Fluorine Binding Sites List in 3gp0
Fluorine binding site 2 out
of 3 in the Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 3gp0Go back to Fluorine Binding Sites List in 3gp0
Fluorine binding site 3 out
of 3 in the Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib
Mono view Stereo pair view
Reference:
P.Filippakopoulos,
A.Barr,
O.Fedorov,
T.Keates,
M.Soundararajan,
J.Elkins,
E.Salah,
N.Burgess-Brown,
E.Ugochukwu,
A.C.W.Pike,
J.Muniz,
A.Roos,
A.Chaikuad,
F.Von Delft,
C.H.Arrowsmith,
A.M.Edwards,
J.Weigelt,
C.Bountra,
S.Knapp,
Structural Genomics Consortium (Sgc).
Crystal Structure of Human Mitogen Activated Protein Kinase 11 (P38 Beta) in Complex with Nilotinib To Be Published.
Page generated: Sun Dec 13 11:47:09 2020
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