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Atomistry » Fluorine » PDB 3gww-3hkw » 3h9k » |
Fluorine in PDB 3h9k: Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit AsymmetryEnzymatic activity of Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry
All present enzymatic activity of Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry:
2.1.1.45; Protein crystallography data
The structure of Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry, PDB code: 3h9k
was solved by
L.M.Gibson,
L.L.Lovelace,
L.Lebioda,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry
(pdb code 3h9k). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry, PDB code: 3h9k: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 3h9kGo back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 3h9kGo back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 3h9kGo back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry
![]() Mono view ![]() Stereo pair view
Reference:
L.M.Gibson,
L.R.Celeste,
L.L.Lovelace,
L.Lebioda.
Structures of Human Thymidylate Synthase R163K with Dump, Fdump and Glutathione Show Asymmetric Ligand Binding. Acta Crystallogr.,Sect.D V. 67 60 2011.
Page generated: Mon Jul 14 16:45:42 2025
ISSN: ISSN 0907-4449 PubMed: 21206062 DOI: 10.1107/S0907444910044732 |
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