Fluorine in PDB 3hb0: Structure of EDEYA2 Complexed with BEF3
Enzymatic activity of Structure of EDEYA2 Complexed with BEF3
All present enzymatic activity of Structure of EDEYA2 Complexed with BEF3:
3.1.3.48;
Protein crystallography data
The structure of Structure of EDEYA2 Complexed with BEF3, PDB code: 3hb0
was solved by
S.K.Jung,
D.G.Jeong,
S.E.Ryu,
S.J.Kim,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
40.00 /
2.50
|
|
Space group
|
I 4
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
184.002,
184.002,
119.954,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
22.4 /
25.4
|
Other elements in 3hb0:
The structure of Structure of EDEYA2 Complexed with BEF3 also contains other interesting chemical elements:
Fluorine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Fluorine atom in the Structure of EDEYA2 Complexed with BEF3
(pdb code 3hb0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the
Structure of EDEYA2 Complexed with BEF3, PDB code: 3hb0:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Fluorine binding site 1 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 1 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F801
b:33.9
occ:1.00
|
F1
|
A:BEF801
|
0.0
|
33.9
|
1.0
|
|
BE
|
A:BEF801
|
1.4
|
33.9
|
1.0
|
|
F3
|
A:BEF801
|
2.3
|
34.7
|
1.0
|
|
F2
|
A:BEF801
|
2.3
|
36.3
|
1.0
|
|
OD1
|
A:ASP274
|
2.4
|
31.1
|
1.0
|
|
N
|
A:THR448
|
2.9
|
34.9
|
1.0
|
|
OG1
|
A:THR448
|
3.0
|
40.8
|
1.0
|
|
NZ
|
A:LYS480
|
3.2
|
37.3
|
1.0
|
|
O
|
A:HOH71
|
3.2
|
29.7
|
1.0
|
|
CA
|
A:THR447
|
3.5
|
33.3
|
1.0
|
|
OG1
|
A:THR447
|
3.6
|
34.0
|
1.0
|
|
CG
|
A:ASP274
|
3.6
|
29.6
|
1.0
|
|
CE
|
A:LYS480
|
3.6
|
36.0
|
1.0
|
|
C
|
A:THR447
|
3.7
|
34.6
|
1.0
|
|
O
|
A:HOH111
|
3.8
|
42.1
|
1.0
|
|
CB
|
A:THR448
|
3.8
|
36.8
|
1.0
|
|
O
|
A:HOH110
|
3.9
|
49.2
|
1.0
|
|
CA
|
A:THR448
|
3.9
|
36.3
|
1.0
|
|
CG2
|
A:THR448
|
4.0
|
37.3
|
1.0
|
|
CB
|
A:THR447
|
4.1
|
33.4
|
1.0
|
|
OD2
|
A:ASP274
|
4.1
|
30.1
|
1.0
|
|
MG
|
A:MG701
|
4.1
|
36.5
|
1.0
|
|
O
|
A:VAL446
|
4.3
|
33.9
|
1.0
|
|
OE2
|
A:GLU506
|
4.4
|
44.3
|
1.0
|
|
OD1
|
A:ASP276
|
4.4
|
32.1
|
1.0
|
|
N
|
A:THR447
|
4.7
|
31.8
|
1.0
|
|
N
|
A:LEU275
|
4.7
|
28.1
|
1.0
|
|
CB
|
A:ASP274
|
4.8
|
26.6
|
1.0
|
|
N
|
A:THR449
|
4.9
|
33.8
|
1.0
|
|
C
|
A:VAL446
|
4.9
|
31.6
|
1.0
|
|
O
|
A:THR447
|
4.9
|
36.5
|
1.0
|
|
N
|
A:ASP276
|
4.9
|
29.6
|
1.0
|
|
C
|
A:THR448
|
4.9
|
36.2
|
1.0
|
|
Fluorine binding site 2 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 2 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F801
b:36.3
occ:1.00
|
F2
|
A:BEF801
|
0.0
|
36.3
|
1.0
|
|
BE
|
A:BEF801
|
1.4
|
33.9
|
1.0
|
|
MG
|
A:MG701
|
2.1
|
36.5
|
1.0
|
|
F1
|
A:BEF801
|
2.3
|
33.9
|
1.0
|
|
F3
|
A:BEF801
|
2.4
|
34.7
|
1.0
|
|
OD1
|
A:ASP274
|
2.5
|
31.1
|
1.0
|
|
OD2
|
A:ASP274
|
2.6
|
30.1
|
1.0
|
|
CG
|
A:ASP274
|
2.9
|
29.6
|
1.0
|
|
O
|
A:ASP276
|
3.1
|
34.4
|
1.0
|
|
O
|
A:HOH126
|
3.2
|
28.2
|
1.0
|
|
O
|
A:HOH111
|
3.4
|
42.1
|
1.0
|
|
CB
|
A:ASP276
|
3.4
|
29.0
|
1.0
|
|
N
|
A:ASP276
|
3.5
|
29.6
|
1.0
|
|
CA
|
A:ASP276
|
3.7
|
30.3
|
1.0
|
|
C
|
A:ASP276
|
3.8
|
31.6
|
1.0
|
|
O
|
A:HOH71
|
3.9
|
29.7
|
1.0
|
|
OD1
|
A:ASP276
|
3.9
|
32.1
|
1.0
|
|
OE2
|
A:GLU506
|
4.0
|
44.3
|
1.0
|
|
O
|
A:HOH110
|
4.1
|
49.2
|
1.0
|
|
OD1
|
A:ASP502
|
4.1
|
36.0
|
1.0
|
|
CG
|
A:ASP276
|
4.2
|
30.9
|
1.0
|
|
OG1
|
A:THR448
|
4.3
|
40.8
|
1.0
|
|
N
|
A:LEU275
|
4.3
|
28.1
|
1.0
|
|
CB
|
A:ASP274
|
4.4
|
26.6
|
1.0
|
|
NZ
|
A:LYS480
|
4.4
|
37.3
|
1.0
|
|
C
|
A:LEU275
|
4.5
|
29.4
|
1.0
|
|
OG1
|
A:THR447
|
4.7
|
34.0
|
1.0
|
|
O
|
A:HOH133
|
4.9
|
27.7
|
1.0
|
|
CA
|
A:LEU275
|
4.9
|
27.6
|
1.0
|
|
Fluorine binding site 3 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 3 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F801
b:34.7
occ:1.00
|
F3
|
A:BEF801
|
0.0
|
34.7
|
1.0
|
|
BE
|
A:BEF801
|
1.4
|
33.9
|
1.0
|
|
F1
|
A:BEF801
|
2.3
|
33.9
|
1.0
|
|
F2
|
A:BEF801
|
2.4
|
36.3
|
1.0
|
|
OD1
|
A:ASP274
|
2.4
|
31.1
|
1.0
|
|
N
|
A:LEU275
|
2.8
|
28.1
|
1.0
|
|
OG1
|
A:THR447
|
2.8
|
34.0
|
1.0
|
|
N
|
A:ASP276
|
2.9
|
29.6
|
1.0
|
|
CG
|
A:ASP274
|
3.1
|
29.6
|
1.0
|
|
OD1
|
A:ASP276
|
3.3
|
32.1
|
1.0
|
|
CB
|
A:THR447
|
3.3
|
33.4
|
1.0
|
|
CA
|
A:LEU275
|
3.4
|
27.6
|
1.0
|
|
CB
|
A:LEU275
|
3.4
|
24.5
|
1.0
|
|
OD2
|
A:ASP274
|
3.4
|
30.1
|
1.0
|
|
C
|
A:LEU275
|
3.6
|
29.4
|
1.0
|
|
CA
|
A:THR447
|
3.6
|
33.3
|
1.0
|
|
CB
|
A:ASP276
|
3.8
|
29.0
|
1.0
|
|
C
|
A:ASP274
|
3.9
|
27.8
|
1.0
|
|
CA
|
A:ASP276
|
3.9
|
30.3
|
1.0
|
|
CG
|
A:ASP276
|
3.9
|
30.9
|
1.0
|
|
N
|
A:THR448
|
4.1
|
34.9
|
1.0
|
|
MG
|
A:MG701
|
4.2
|
36.5
|
1.0
|
|
CA
|
A:ASP274
|
4.2
|
27.5
|
1.0
|
|
O
|
A:HOH110
|
4.2
|
49.2
|
1.0
|
|
O
|
A:VAL446
|
4.2
|
33.9
|
1.0
|
|
CB
|
A:ASP274
|
4.2
|
26.6
|
1.0
|
|
O
|
A:ASP276
|
4.3
|
34.4
|
1.0
|
|
C
|
A:THR447
|
4.4
|
34.6
|
1.0
|
|
CG
|
A:LEU275
|
4.5
|
21.3
|
1.0
|
|
C
|
A:ASP276
|
4.6
|
31.6
|
1.0
|
|
OG1
|
A:THR448
|
4.7
|
40.8
|
1.0
|
|
N
|
A:THR447
|
4.7
|
31.8
|
1.0
|
|
O
|
A:LEU275
|
4.7
|
31.4
|
1.0
|
|
CG2
|
A:THR447
|
4.8
|
30.6
|
1.0
|
|
NZ
|
A:LYS480
|
4.8
|
37.3
|
1.0
|
|
C
|
A:VAL446
|
4.9
|
31.6
|
1.0
|
|
O
|
A:ASP274
|
5.0
|
27.4
|
1.0
|
|
CD2
|
A:LEU275
|
5.0
|
24.2
|
1.0
|
|
OD2
|
A:ASP276
|
5.0
|
29.0
|
1.0
|
|
Fluorine binding site 4 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 4 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F802
b:44.7
occ:1.00
|
F1
|
B:BEF802
|
0.0
|
44.7
|
1.0
|
|
BE
|
B:BEF802
|
1.4
|
43.5
|
1.0
|
|
F2
|
B:BEF802
|
2.3
|
44.4
|
1.0
|
|
F3
|
B:BEF802
|
2.3
|
43.0
|
1.0
|
|
OD1
|
B:ASP274
|
2.4
|
42.3
|
1.0
|
|
NZ
|
B:LYS480
|
2.9
|
45.8
|
1.0
|
|
N
|
B:THR448
|
2.9
|
42.5
|
1.0
|
|
O
|
B:HOH60
|
3.1
|
36.9
|
1.0
|
|
CB
|
B:THR448
|
3.5
|
45.8
|
1.0
|
|
CE
|
B:LYS480
|
3.5
|
47.9
|
1.0
|
|
OG1
|
B:THR448
|
3.6
|
47.2
|
1.0
|
|
CG
|
B:ASP274
|
3.6
|
39.7
|
1.0
|
|
CA
|
B:THR447
|
3.6
|
39.1
|
1.0
|
|
C
|
B:THR447
|
3.8
|
41.8
|
1.0
|
|
O
|
B:HOH136
|
3.8
|
45.7
|
1.0
|
|
CA
|
B:THR448
|
3.8
|
43.8
|
1.0
|
|
OG1
|
B:THR447
|
3.8
|
39.2
|
1.0
|
|
MG
|
B:MG702
|
4.0
|
44.1
|
1.0
|
|
OD2
|
B:ASP274
|
4.1
|
39.9
|
1.0
|
|
CB
|
B:THR447
|
4.2
|
38.1
|
1.0
|
|
O
|
B:VAL446
|
4.3
|
35.9
|
1.0
|
|
O
|
B:HOH132
|
4.6
|
64.9
|
1.0
|
|
OD1
|
B:ASP276
|
4.7
|
46.2
|
1.0
|
|
OE2
|
B:GLU506
|
4.7
|
57.4
|
1.0
|
|
N
|
B:THR447
|
4.8
|
37.6
|
1.0
|
|
CB
|
B:ASP274
|
4.8
|
36.5
|
1.0
|
|
N
|
B:LEU275
|
4.8
|
35.3
|
1.0
|
|
CG2
|
B:THR448
|
4.8
|
46.6
|
1.0
|
|
C
|
B:THR448
|
4.9
|
44.9
|
1.0
|
|
O
|
B:THR447
|
5.0
|
42.7
|
1.0
|
|
N
|
B:ASP276
|
5.0
|
35.6
|
1.0
|
|
N
|
B:THR449
|
5.0
|
44.0
|
1.0
|
|
CD
|
B:LYS480
|
5.0
|
49.8
|
1.0
|
|
C
|
B:VAL446
|
5.0
|
36.9
|
1.0
|
|
Fluorine binding site 5 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 5 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F802
b:44.4
occ:1.00
|
F2
|
B:BEF802
|
0.0
|
44.4
|
1.0
|
|
BE
|
B:BEF802
|
1.4
|
43.5
|
1.0
|
|
MG
|
B:MG702
|
1.9
|
44.1
|
1.0
|
|
F1
|
B:BEF802
|
2.3
|
44.7
|
1.0
|
|
F3
|
B:BEF802
|
2.3
|
43.0
|
1.0
|
|
OD1
|
B:ASP274
|
2.5
|
42.3
|
1.0
|
|
OD2
|
B:ASP274
|
2.6
|
39.9
|
1.0
|
|
O
|
B:HOH132
|
2.8
|
64.9
|
1.0
|
|
CG
|
B:ASP274
|
2.8
|
39.7
|
1.0
|
|
O
|
B:ASP276
|
3.0
|
36.1
|
1.0
|
|
O
|
B:HOH60
|
3.4
|
36.9
|
1.0
|
|
CB
|
B:ASP276
|
3.5
|
40.3
|
1.0
|
|
N
|
B:ASP276
|
3.6
|
35.6
|
1.0
|
|
C
|
B:ASP276
|
3.7
|
37.4
|
1.0
|
|
CA
|
B:ASP276
|
3.8
|
37.7
|
1.0
|
|
O
|
B:HOH135
|
3.8
|
51.1
|
1.0
|
|
O
|
B:HOH136
|
3.9
|
45.7
|
1.0
|
|
OD1
|
B:ASP502
|
4.0
|
36.4
|
1.0
|
|
OD1
|
B:ASP276
|
4.2
|
46.2
|
1.0
|
|
NZ
|
B:LYS480
|
4.3
|
45.8
|
1.0
|
|
CB
|
B:ASP274
|
4.4
|
36.5
|
1.0
|
|
CG
|
B:ASP276
|
4.4
|
43.5
|
1.0
|
|
N
|
B:LEU275
|
4.4
|
35.3
|
1.0
|
|
C
|
B:LEU275
|
4.5
|
35.2
|
1.0
|
|
O
|
B:HOH134
|
4.5
|
40.4
|
1.0
|
|
OE2
|
B:GLU506
|
4.6
|
57.4
|
1.0
|
|
O
|
B:HOH86
|
4.8
|
42.1
|
1.0
|
|
OG1
|
B:THR447
|
5.0
|
39.2
|
1.0
|
|
Fluorine binding site 6 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 6 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F802
b:43.0
occ:1.00
|
F3
|
B:BEF802
|
0.0
|
43.0
|
1.0
|
|
BE
|
B:BEF802
|
1.4
|
43.5
|
1.0
|
|
F2
|
B:BEF802
|
2.3
|
44.4
|
1.0
|
|
F1
|
B:BEF802
|
2.3
|
44.7
|
1.0
|
|
OD1
|
B:ASP274
|
2.5
|
42.3
|
1.0
|
|
N
|
B:ASP276
|
2.8
|
35.6
|
1.0
|
|
OG1
|
B:THR447
|
3.0
|
39.2
|
1.0
|
|
N
|
B:LEU275
|
3.1
|
35.3
|
1.0
|
|
OD1
|
B:ASP276
|
3.1
|
46.2
|
1.0
|
|
CG
|
B:ASP274
|
3.2
|
39.7
|
1.0
|
|
CB
|
B:THR447
|
3.4
|
38.1
|
1.0
|
|
CB
|
B:LEU275
|
3.5
|
34.1
|
1.0
|
|
CA
|
B:LEU275
|
3.5
|
34.5
|
1.0
|
|
OD2
|
B:ASP274
|
3.5
|
39.9
|
1.0
|
|
C
|
B:LEU275
|
3.6
|
35.2
|
1.0
|
|
CB
|
B:ASP276
|
3.6
|
40.3
|
1.0
|
|
CA
|
B:THR447
|
3.7
|
39.1
|
1.0
|
|
O
|
B:HOH136
|
3.7
|
45.7
|
1.0
|
|
CA
|
B:ASP276
|
3.7
|
37.7
|
1.0
|
|
CG
|
B:ASP276
|
3.8
|
43.5
|
1.0
|
|
N
|
B:THR448
|
4.0
|
42.5
|
1.0
|
|
MG
|
B:MG702
|
4.1
|
44.1
|
1.0
|
|
C
|
B:ASP274
|
4.1
|
36.1
|
1.0
|
|
O
|
B:ASP276
|
4.2
|
36.1
|
1.0
|
|
O
|
B:VAL446
|
4.4
|
35.9
|
1.0
|
|
C
|
B:THR447
|
4.4
|
41.8
|
1.0
|
|
CB
|
B:ASP274
|
4.4
|
36.5
|
1.0
|
|
C
|
B:ASP276
|
4.5
|
37.4
|
1.0
|
|
CA
|
B:ASP274
|
4.5
|
35.4
|
1.0
|
|
CG
|
B:LEU275
|
4.6
|
33.5
|
1.0
|
|
O
|
B:LEU275
|
4.7
|
35.6
|
1.0
|
|
NZ
|
B:LYS480
|
4.7
|
45.8
|
1.0
|
|
N
|
B:THR447
|
4.8
|
37.6
|
1.0
|
|
CG2
|
B:THR447
|
4.8
|
36.5
|
1.0
|
|
OD2
|
B:ASP276
|
4.9
|
44.3
|
1.0
|
|
OG1
|
B:THR449
|
4.9
|
43.3
|
1.0
|
|
O
|
B:HOH132
|
5.0
|
64.9
|
1.0
|
|
Fluorine binding site 7 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 7 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F803
b:41.6
occ:1.00
|
F1
|
C:BEF803
|
0.0
|
41.6
|
1.0
|
|
BE
|
C:BEF803
|
1.4
|
40.5
|
1.0
|
|
F3
|
C:BEF803
|
2.3
|
40.1
|
1.0
|
|
F2
|
C:BEF803
|
2.3
|
41.3
|
1.0
|
|
OD1
|
C:ASP274
|
2.5
|
38.8
|
1.0
|
|
NZ
|
C:LYS480
|
2.9
|
41.0
|
1.0
|
|
N
|
C:THR448
|
3.0
|
43.8
|
1.0
|
|
OG1
|
C:THR448
|
3.2
|
47.4
|
1.0
|
|
CE
|
C:LYS480
|
3.4
|
44.0
|
1.0
|
|
CG
|
C:ASP274
|
3.6
|
36.2
|
1.0
|
|
CA
|
C:THR447
|
3.6
|
40.7
|
1.0
|
|
CG2
|
C:THR448
|
3.7
|
42.9
|
1.0
|
|
OG1
|
C:THR447
|
3.8
|
38.6
|
1.0
|
|
CB
|
C:THR448
|
3.8
|
43.3
|
1.0
|
|
C
|
C:THR447
|
3.8
|
42.7
|
1.0
|
|
CA
|
C:THR448
|
4.0
|
43.6
|
1.0
|
|
OD2
|
C:ASP274
|
4.1
|
37.8
|
1.0
|
|
MG
|
C:MG703
|
4.1
|
39.3
|
1.0
|
|
CB
|
C:THR447
|
4.2
|
39.6
|
1.0
|
|
O
|
C:VAL446
|
4.3
|
43.0
|
1.0
|
|
OD1
|
C:ASP276
|
4.5
|
45.0
|
1.0
|
|
N
|
C:LEU275
|
4.7
|
37.5
|
1.0
|
|
N
|
C:THR447
|
4.8
|
40.8
|
1.0
|
|
OE2
|
C:GLU506
|
4.8
|
53.9
|
1.0
|
|
CB
|
C:ASP274
|
4.8
|
36.3
|
1.0
|
|
N
|
C:THR449
|
4.9
|
43.7
|
1.0
|
|
CD
|
C:LYS480
|
4.9
|
44.0
|
1.0
|
|
N
|
C:ASP276
|
4.9
|
38.9
|
1.0
|
|
C
|
C:THR448
|
5.0
|
43.8
|
1.0
|
|
C
|
C:VAL446
|
5.0
|
41.2
|
1.0
|
|
O
|
C:THR447
|
5.0
|
43.0
|
1.0
|
|
Fluorine binding site 8 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 8 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F803
b:41.3
occ:1.00
|
F2
|
C:BEF803
|
0.0
|
41.3
|
1.0
|
|
BE
|
C:BEF803
|
1.4
|
40.5
|
1.0
|
|
MG
|
C:MG703
|
2.1
|
39.3
|
1.0
|
|
F1
|
C:BEF803
|
2.3
|
41.6
|
1.0
|
|
F3
|
C:BEF803
|
2.3
|
40.1
|
1.0
|
|
OD1
|
C:ASP274
|
2.5
|
38.8
|
1.0
|
|
OD2
|
C:ASP274
|
2.6
|
37.8
|
1.0
|
|
CG
|
C:ASP274
|
2.9
|
36.2
|
1.0
|
|
O
|
C:ASP276
|
3.0
|
38.7
|
1.0
|
|
O
|
C:HOH129
|
3.3
|
29.8
|
1.0
|
|
CB
|
C:ASP276
|
3.5
|
38.9
|
1.0
|
|
N
|
C:ASP276
|
3.5
|
38.9
|
1.0
|
|
CA
|
C:ASP276
|
3.7
|
38.3
|
1.0
|
|
C
|
C:ASP276
|
3.8
|
38.6
|
1.0
|
|
OD1
|
C:ASP276
|
4.0
|
45.0
|
1.0
|
|
OD1
|
C:ASP502
|
4.1
|
38.7
|
1.0
|
|
NZ
|
C:LYS480
|
4.3
|
41.0
|
1.0
|
|
CG
|
C:ASP276
|
4.3
|
41.5
|
1.0
|
|
N
|
C:LEU275
|
4.3
|
37.5
|
1.0
|
|
OE2
|
C:GLU506
|
4.3
|
53.9
|
1.0
|
|
CB
|
C:ASP274
|
4.4
|
36.3
|
1.0
|
|
C
|
C:LEU275
|
4.4
|
39.2
|
1.0
|
|
OG1
|
C:THR448
|
4.6
|
47.4
|
1.0
|
|
O
|
C:HOH137
|
4.9
|
36.5
|
1.0
|
|
CA
|
C:LEU275
|
4.9
|
37.4
|
1.0
|
|
OG1
|
C:THR447
|
4.9
|
38.6
|
1.0
|
|
Fluorine binding site 9 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 9 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 9 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F803
b:40.1
occ:1.00
|
F3
|
C:BEF803
|
0.0
|
40.1
|
1.0
|
|
BE
|
C:BEF803
|
1.4
|
40.5
|
1.0
|
|
F1
|
C:BEF803
|
2.3
|
41.6
|
1.0
|
|
F2
|
C:BEF803
|
2.3
|
41.3
|
1.0
|
|
OD1
|
C:ASP274
|
2.4
|
38.8
|
1.0
|
|
N
|
C:LEU275
|
2.8
|
37.5
|
1.0
|
|
N
|
C:ASP276
|
2.9
|
38.9
|
1.0
|
|
OG1
|
C:THR447
|
3.0
|
38.6
|
1.0
|
|
CG
|
C:ASP274
|
3.1
|
36.2
|
1.0
|
|
OD1
|
C:ASP276
|
3.3
|
45.0
|
1.0
|
|
CA
|
C:LEU275
|
3.3
|
37.4
|
1.0
|
|
CB
|
C:THR447
|
3.4
|
39.6
|
1.0
|
|
CB
|
C:LEU275
|
3.4
|
36.2
|
1.0
|
|
OD2
|
C:ASP274
|
3.4
|
37.8
|
1.0
|
|
C
|
C:LEU275
|
3.5
|
39.2
|
1.0
|
|
CA
|
C:THR447
|
3.6
|
40.7
|
1.0
|
|
C
|
C:ASP274
|
3.9
|
37.4
|
1.0
|
|
CA
|
C:ASP276
|
3.9
|
38.3
|
1.0
|
|
CB
|
C:ASP276
|
3.9
|
38.9
|
1.0
|
|
CG
|
C:ASP276
|
4.0
|
41.5
|
1.0
|
|
N
|
C:THR448
|
4.1
|
43.8
|
1.0
|
|
O
|
C:VAL446
|
4.1
|
43.0
|
1.0
|
|
CA
|
C:ASP274
|
4.2
|
36.9
|
1.0
|
|
MG
|
C:MG703
|
4.2
|
39.3
|
1.0
|
|
CB
|
C:ASP274
|
4.2
|
36.3
|
1.0
|
|
O
|
C:ASP276
|
4.3
|
38.7
|
1.0
|
|
C
|
C:THR447
|
4.4
|
42.7
|
1.0
|
|
NZ
|
C:LYS480
|
4.4
|
41.0
|
1.0
|
|
CG
|
C:LEU275
|
4.6
|
35.0
|
1.0
|
|
C
|
C:ASP276
|
4.6
|
38.6
|
1.0
|
|
N
|
C:THR447
|
4.7
|
40.8
|
1.0
|
|
O
|
C:LEU275
|
4.7
|
42.0
|
1.0
|
|
OG1
|
C:THR448
|
4.8
|
47.4
|
1.0
|
|
CG2
|
C:THR447
|
4.8
|
40.1
|
1.0
|
|
C
|
C:VAL446
|
4.8
|
41.2
|
1.0
|
|
O
|
C:ASP274
|
5.0
|
36.8
|
1.0
|
|
OG1
|
C:THR449
|
5.0
|
45.8
|
1.0
|
|
Fluorine binding site 10 out
of 12 in 3hb0
Go back to
Fluorine Binding Sites List in 3hb0
Fluorine binding site 10 out
of 12 in the Structure of EDEYA2 Complexed with BEF3
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 10 of Structure of EDEYA2 Complexed with BEF3 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F804
b:39.1
occ:1.00
|
F1
|
D:BEF804
|
0.0
|
39.1
|
1.0
|
|
BE
|
D:BEF804
|
1.4
|
36.5
|
1.0
|
|
F2
|
D:BEF804
|
2.3
|
37.3
|
1.0
|
|
F3
|
D:BEF804
|
2.3
|
35.7
|
1.0
|
|
OD1
|
D:ASP274
|
2.4
|
35.5
|
1.0
|
|
NZ
|
D:LYS480
|
2.9
|
31.2
|
1.0
|
|
N
|
D:THR448
|
3.0
|
37.8
|
1.0
|
|
OG1
|
D:THR448
|
3.4
|
41.4
|
1.0
|
|
CE
|
D:LYS480
|
3.5
|
33.9
|
1.0
|
|
CA
|
D:THR447
|
3.6
|
35.9
|
1.0
|
|
CG
|
D:ASP274
|
3.6
|
34.3
|
1.0
|
|
OG1
|
D:THR447
|
3.6
|
36.7
|
1.0
|
|
O
|
D:HOH130
|
3.7
|
42.9
|
1.0
|
|
C
|
D:THR447
|
3.8
|
38.4
|
1.0
|
|
CB
|
D:THR448
|
3.8
|
38.8
|
1.0
|
|
CA
|
D:THR448
|
4.0
|
37.9
|
1.0
|
|
MG
|
D:MG704
|
4.0
|
43.9
|
1.0
|
|
CB
|
D:THR447
|
4.1
|
34.6
|
1.0
|
|
OD2
|
D:ASP274
|
4.1
|
37.2
|
1.0
|
|
O
|
D:VAL446
|
4.3
|
38.5
|
1.0
|
|
OE2
|
D:GLU506
|
4.4
|
49.0
|
1.0
|
|
OD1
|
D:ASP276
|
4.6
|
45.1
|
1.0
|
|
N
|
D:THR447
|
4.7
|
36.3
|
1.0
|
|
N
|
D:LEU275
|
4.7
|
34.3
|
1.0
|
|
O
|
D:HOH138
|
4.8
|
45.2
|
1.0
|
|
N
|
D:ASP276
|
4.8
|
35.7
|
1.0
|
|
CB
|
D:ASP274
|
4.8
|
29.8
|
1.0
|
|
CB
|
D:ASP276
|
4.9
|
38.3
|
1.0
|
|
N
|
D:THR449
|
4.9
|
37.9
|
1.0
|
|
C
|
D:VAL446
|
5.0
|
36.1
|
1.0
|
|
O
|
D:THR447
|
5.0
|
39.7
|
1.0
|
|
CD
|
D:LYS480
|
5.0
|
36.5
|
1.0
|
|
Reference:
S.K.Jung,
D.G.Jeong,
S.J.Chung,
J.H.Kim,
B.C.Park,
N.K.Tonks,
S.E.Ryu,
S.J.Kim.
Crystal Structure of Ed-EYA2: Insight Into Dual Roles As A Protein Tyrosine Phosphatase and A Transcription Factor Faseb J. V. 24 560 2010.
ISSN: ISSN 0892-6638
PubMed: 19858093
DOI: 10.1096/FJ.09-143891
Page generated: Wed Jul 31 19:10:15 2024
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