Fluorine in PDB 3hjw: Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna

The structure of Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna, PDB code: 3hjw was solved by B.Liang, J.Zhou, E.Kahen, R.M.Terns, M.P.Terns, H.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.52 / 2.35
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	186.013, 63.026, 85.447, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 24.8

The structure of Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna also contains other interesting chemical elements:

Potassium	(K)	1 atom
Zinc	(Zn)	1 atom

The binding sites of Fluorine atom in the Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna (pdb code 3hjw). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna, PDB code: 3hjw:

Fluorine binding site 1 out of 1 in the Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna within 5.0Å range: probe atom residue distance (Å) B Occ E:F10 b:38.6 occ:1.00 F5 E:FHU10 0.0 38.6 1.0 C5 E:FHU10 1.3 36.7 1.0 C6 E:FHU10 2.3 37.0 1.0 C4 E:FHU10 2.3 38.0 1.0 C1' E:FHU10 2.4 32.7 1.0 O6 E:FHU10 2.5 37.4 1.0 O4' E:FHU10 2.6 29.6 1.0 O4 E:FHU10 2.7 37.0 1.0 K E:K2 3.1 41.9 1.0 OH A:TYR113 3.2 27.0 1.0 C2' E:FHU10 3.2 30.6 1.0 N3 E:FHU10 3.5 39.1 1.0 C4' E:FHU10 3.5 26.9 1.0 N1 E:FHU10 3.6 37.7 1.0 C5' E:FHU10 3.6 22.7 1.0 O5' E:FHU10 3.8 18.3 1.0 CZ A:TYR113 3.8 23.4 1.0 C2 E:FHU10 3.9 38.5 1.0 C3' E:FHU10 4.0 29.0 1.0 CE2 A:TYR113 4.1 21.4 1.0 O2' E:FHU10 4.3 32.1 1.0 O A:THR83 4.3 22.7 1.0 O E:HOH63 4.6 46.1 1.0 O A:THR181 4.8 21.8 1.0 CE1 A:TYR113 4.8 22.2 1.0 CD2 A:LEU203 4.9 18.7 1.0 CD2 A:LEU84 4.9 17.8 1.0 O2 E:FHU10 5.0 39.5 1.0 CG1 A:ILE183 5.0 24.1 1.0 P E:FHU10 5.0 13.4 1.0

B.Liang, J.Zhou, E.Kahen, R.M.Terns, M.P.Terns, H.Li. Structure of A Functional Ribonucleoprotein Pseudouridine Synthase Bound to A Substrate Rna Nat.Struct.Mol.Biol. V. 16 740 2009.
ISSN: ISSN 1545-9993
PubMed: 19478803
DOI: 10.1038/NSMB.1624