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Atomistry » Fluorine » PDB 3igu-3jx2 » 3iro » |
Fluorine in PDB 3iro: Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 AntifolateEnzymatic activity of Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate
All present enzymatic activity of Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate:
1.5.1.3; 2.1.1.45; Protein crystallography data
The structure of Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate, PDB code: 3iro
was solved by
P.Chitnumsub,
J.Yuvaniyama,
Y.Yuthavong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate
(pdb code 3iro). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate, PDB code: 3iro: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 3iroGo back to Fluorine Binding Sites List in 3iro
Fluorine binding site 1 out
of 4 in the Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 3iroGo back to Fluorine Binding Sites List in 3iro
Fluorine binding site 2 out
of 4 in the Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 3iroGo back to Fluorine Binding Sites List in 3iro
Fluorine binding site 3 out
of 4 in the Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 3iroGo back to Fluorine Binding Sites List in 3iro
Fluorine binding site 4 out
of 4 in the Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed with Nadph and Q-8 Antifolate
Mono view Stereo pair view
Reference:
P.Chitnumsub,
J.Yuvaniyama,
T.Vilaivan,
J.Vanichtanankul,
S.Kamchonwongpaisan,
Y.Yuthavong.
Structural Basis of Antifolate Inhibition of Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase To Be Published.
Page generated: Wed Jul 31 19:35:15 2024
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