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Atomistry » Fluorine » PDB 3igu-3jx2 » 3jpt » |
Fluorine in PDB 3jpt: Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene TriphosphateEnzymatic activity of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate
All present enzymatic activity of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate:
2.7.7.7; Protein crystallography data
The structure of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate, PDB code: 3jpt
was solved by
V.K.Batra,
J.Upton,
B.Kashmerov,
W.A.Beard,
S.H.Wilson,
M.F.Goodman,
C.E.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3jpt:
The structure of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate
(pdb code 3jpt). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate, PDB code: 3jpt: Fluorine binding site 1 out of 1 in 3jptGo back to Fluorine Binding Sites List in 3jpt
Fluorine binding site 1 out
of 1 in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate
Mono view Stereo pair view
Reference:
V.K.Batra,
L.C.Pedersen,
W.A.Beard,
S.H.Wilson,
B.A.Kashemirov,
T.G.Upton,
M.F.Goodman,
C.E.Mckenna.
Halogenated Beta,Gamma-Methylene- and Ethylidene-Dgtp-Dna Ternary Complexes with Dna Polymerase Beta: Structural Evidence For Stereospecific Binding of the Fluoromethylene Analogues. J.Am.Chem.Soc. V. 132 7617 2010.
Page generated: Sun Dec 13 11:48:43 2020
ISSN: ISSN 0002-7863 PubMed: 20465217 DOI: 10.1021/JA909370K |
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