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Atomistry » Fluorine » PDB 3jx3-3kql » 3khm » |
Fluorine in PDB 3khm: Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor FluconazoleEnzymatic activity of Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole
All present enzymatic activity of Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole:
1.14.13.70; Protein crystallography data
The structure of Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole, PDB code: 3khm
was solved by
G.I.Lepesheva,
T.Y.Hargrove,
S.Anderson,
Z.Wawrzak,
M.R.Waterman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3khm:
The structure of Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole
(pdb code 3khm). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole, PDB code: 3khm: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 3khmGo back to Fluorine Binding Sites List in 3khm
Fluorine binding site 1 out
of 2 in the Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 3khmGo back to Fluorine Binding Sites List in 3khm
Fluorine binding site 2 out
of 2 in the Crystal Structure of Sterol 14ALPHA-Demethylase (CYP51) From Trypanosoma Cruzi in Complex with Inhibitor Fluconazole
Mono view Stereo pair view
Reference:
G.I.Lepesheva,
T.Y.Hargrove,
S.Anderson,
Y.Kleshchenko,
V.Furtak,
Z.Wawrzak,
F.Villalta,
M.R.Waterman.
Structural Insights Into Inhibition of Sterol 14{Alpha}-Demethylase in the Human Pathogen Trypanosoma Cruzi. J.Biol.Chem. V. 285 25582 2010.
Page generated: Wed Jul 31 19:53:41 2024
ISSN: ISSN 0021-9258 PubMed: 20530488 DOI: 10.1074/JBC.M110.133215 |
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