Fluorine in PDB 3l2v: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir)

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir), PDB code: 3l2v was solved by S.Hare, S.S.Gupta, P.Cherepanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.48 / 3.20
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	158.650, 158.650, 125.230, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 23.2

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir) also contains other interesting chemical elements:

Manganese	(Mn)	3 atoms
Zinc	(Zn)	1 atom

The binding sites of Fluorine atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir) (pdb code 3l2v). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir), PDB code: 3l2v:

Fluorine binding site 1 out of 1 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Manganese and MK0518 (Raltegravir) within 5.0Å range: probe atom residue distance (Å) B Occ A:F397 b:76.7 occ:1.00 FAI A:RLT397 0.0 76.7 1.0 CAX A:RLT397 1.4 73.0 1.0 CAJ A:RLT397 2.4 71.5 1.0 CAK A:RLT397 2.4 72.0 1.0 N1 C:DG4 3.3 88.5 1.0 N4 D:DC16 3.3 76.9 1.0 C6 C:DG4 3.3 88.3 1.0 N3 D:DC16 3.4 77.9 1.0 C4 D:DC16 3.4 78.5 1.0 O6 C:DG4 3.5 90.0 1.0 CAL A:RLT397 3.6 70.3 1.0 CAM A:RLT397 3.7 70.9 1.0 CG A:GLN215 3.8 98.2 1.0 CA A:GLN215 3.8 94.8 1.0 N A:GLN215 3.9 94.6 1.0 C2 C:DG4 3.9 88.6 1.0 C5 C:DG4 4.0 87.5 1.0 CB A:GLN215 4.1 95.7 1.0 CAY A:RLT397 4.1 70.4 1.0 C2 D:DC16 4.2 79.5 1.0 C5 D:DC16 4.3 79.9 1.0 C4 C:DG4 4.4 87.7 1.0 N2 C:DG4 4.4 89.4 1.0 C A:PRO214 4.5 94.1 1.0 N3 C:DG4 4.5 88.1 1.0 CB A:PRO214 4.5 93.7 1.0 O2 D:DC16 4.7 78.0 1.0 N7 C:DG4 4.8 87.8 1.0 CD A:GLN215 4.9 0.6 1.0 N1 D:DC16 4.9 81.7 1.0 C6 D:DC16 4.9 81.3 1.0 O A:PRO214 4.9 93.8 1.0

S.Hare, S.S.Gupta, E.Valkov, A.Engelman, P.Cherepanov. Retroviral Intasome Assembly and Inhibition of Dna Strand Transfer Nature V. 464 232 2010.
ISSN: ISSN 0028-0836
PubMed: 20118915
DOI: 10.1038/NATURE08784