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Atomistry » Fluorine » PDB 3l8v-3lxp » 3len » |
Fluorine in PDB 3len: Human Aldose Reductase Mutant T113S Complexed with ZopolrestatEnzymatic activity of Human Aldose Reductase Mutant T113S Complexed with Zopolrestat
All present enzymatic activity of Human Aldose Reductase Mutant T113S Complexed with Zopolrestat:
1.1.1.21; Protein crystallography data
The structure of Human Aldose Reductase Mutant T113S Complexed with Zopolrestat, PDB code: 3len
was solved by
C.Koch,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Aldose Reductase Mutant T113S Complexed with Zopolrestat
(pdb code 3len). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Human Aldose Reductase Mutant T113S Complexed with Zopolrestat, PDB code: 3len: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 3lenGo back to Fluorine Binding Sites List in 3len
Fluorine binding site 1 out
of 3 in the Human Aldose Reductase Mutant T113S Complexed with Zopolrestat
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 3lenGo back to Fluorine Binding Sites List in 3len
Fluorine binding site 2 out
of 3 in the Human Aldose Reductase Mutant T113S Complexed with Zopolrestat
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 3lenGo back to Fluorine Binding Sites List in 3len
Fluorine binding site 3 out
of 3 in the Human Aldose Reductase Mutant T113S Complexed with Zopolrestat
Mono view Stereo pair view
Reference:
C.Koch,
A.Heine,
G.Klebe.
Ligand-Induced Fit Affects Binding Modes and Provokes Changes in Crystal Packing of Aldose Reductase Biochim.Biophys.Acta V.1810 879 2011.
Page generated: Sun Dec 13 11:50:17 2020
ISSN: ISSN 0006-3002 PubMed: 21684320 DOI: 10.1016/J.BBAGEN.2011.06.001 |
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