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Atomistry » Fluorine » PDB 3l8v-3lxp » 3lxl » |
Fluorine in PDB 3lxl: Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6Enzymatic activity of Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6
All present enzymatic activity of Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6:
2.7.10.2; Protein crystallography data
The structure of Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6, PDB code: 3lxl
was solved by
J.E.Chrencik,
T.E.Benson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6
(pdb code 3lxl). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6, PDB code: 3lxl: Fluorine binding site 1 out of 1 in 3lxlGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6
![]() Mono view ![]() Stereo pair view
Reference:
J.E.Chrencik,
A.Patny,
I.K.Leung,
B.Korniski,
T.L.Emmons,
T.Hall,
R.A.Weinberg,
J.A.Gormley,
J.M.Williams,
J.E.Day,
J.L.Hirsch,
J.R.Kiefer,
J.W.Leone,
H.D.Fischer,
C.D.Sommers,
H.C.Huang,
E.J.Jacobsen,
R.E.Tenbrink,
A.G.Tomasselli,
T.E.Benson.
Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with Cp-690550 and Cmp-6. J.Mol.Biol. V. 400 413 2010.
Page generated: Wed Jul 31 20:37:17 2024
ISSN: ISSN 0022-2836 PubMed: 20478313 DOI: 10.1016/J.JMB.2010.05.020 |
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