Fluorine in PDB 3mne: Crystal Structure of the Agonist Form of Mouse Glucocorticoid Receptor Stabilized By F608S Mutation at 1.96A

The structure of Crystal Structure of the Agonist Form of Mouse Glucocorticoid Receptor Stabilized By F608S Mutation at 1.96A, PDB code: 3mne was solved by G.A.Schoch, T.Seitz, J.Benz, D.Banner, M.Stihle, B.D'arcy, R.Thoma, R.Sterner, M.Hennig, A.Ruf, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	12.98 / 1.96
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	71.820, 71.820, 128.650, 90.00, 90.00, 120.00
R / Rfree (%)	15.1 / 18.5

The binding sites of Fluorine atom in the Crystal Structure of the Agonist Form of Mouse Glucocorticoid Receptor Stabilized By F608S Mutation at 1.96A (pdb code 3mne). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Agonist Form of Mouse Glucocorticoid Receptor Stabilized By F608S Mutation at 1.96A, PDB code: 3mne:

Fluorine binding site 1 out of 1 in the Crystal Structure of the Agonist Form of Mouse Glucocorticoid Receptor Stabilized By F608S Mutation at 1.96A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Agonist Form of Mouse Glucocorticoid Receptor Stabilized By F608S Mutation at 1.96A within 5.0Å range: probe atom residue distance (Å) B Occ A:F784 b:18.7 occ:1.00 F1 A:DEX784 0.0 18.7 1.0 C9 A:DEX784 1.4 15.1 1.0 C8 A:DEX784 2.3 13.9 1.0 C10 A:DEX784 2.5 16.8 1.0 C11 A:DEX784 2.5 14.2 1.0 C14 A:DEX784 2.9 15.1 1.0 C5 A:DEX784 2.9 18.2 1.0 C7 A:DEX784 2.9 17.8 1.0 C1 A:DEX784 3.0 21.6 1.0 C12 A:DEX784 3.1 15.8 1.0 CE2 A:PHE629 3.3 21.5 1.0 C6 A:DEX784 3.5 15.0 1.0 C13 A:DEX784 3.5 18.0 1.0 C4 A:DEX784 3.5 19.4 1.0 C2 A:DEX784 3.7 23.2 1.0 O2 A:DEX784 3.8 18.2 1.0 C3 A:DEX784 3.9 23.2 1.0 C19 A:DEX784 3.9 16.6 1.0 CB A:LEU569 4.0 19.8 1.0 CD2 A:PHE629 4.0 21.5 1.0 CD1 A:LEU569 4.0 23.9 1.0 CZ A:PHE629 4.2 20.6 1.0 CE A:MET652 4.3 32.7 1.0 C15 A:DEX784 4.3 15.7 1.0 SD A:MET652 4.4 36.6 1.0 O3 A:DEX784 4.4 20.0 1.0 C17 A:DEX784 4.5 20.5 1.0 CG A:LEU569 4.6 22.6 1.0 C18 A:DEX784 4.7 15.6 1.0 CD2 A:LEU614 4.9 17.0 1.0 O1 A:DEX784 4.9 27.4 1.0 O A:LEU569 5.0 21.6 1.0

T.Seitz, R.Thoma, G.A.Schoch, M.Stihle, J.Benz, B.D'arcy, A.Wiget, A.Ruf, M.Hennig, R.Sterner. Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain By High-Throughput Library Screening. J.Mol.Biol. V. 403 562 2010.
ISSN: ISSN 0022-2836
PubMed: 20850457
DOI: 10.1016/J.JMB.2010.08.048