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Atomistry » Fluorine » PDB 3lz3-3n0n » 3mw1 » |
Fluorine in PDB 3mw1: P38 Kinase Crystal Structure in Complex with Small Molecule InhibitorEnzymatic activity of P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
All present enzymatic activity of P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor:
2.7.11.24; Protein crystallography data
The structure of P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor, PDB code: 3mw1
was solved by
V.Segarra,
F.Caturla,
W.Lumeras,
R.Roca,
M.Fisher,
M.Lamers,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3mw1:
The structure of P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
(pdb code 3mw1). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor, PDB code: 3mw1: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 3mw1Go back to Fluorine Binding Sites List in 3mw1
Fluorine binding site 1 out
of 2 in the P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 3mw1Go back to Fluorine Binding Sites List in 3mw1
Fluorine binding site 2 out
of 2 in the P38 Kinase Crystal Structure in Complex with Small Molecule Inhibitor
Mono view Stereo pair view
Reference:
W.Lumeras,
L.Vidal,
B.Vidal,
C.Balague,
A.Orellana,
M.Maldonado,
M.Dominguez,
V.Segarra,
F.Caturla.
1,7-Naphthyridine 1-Oxides As Novel Potent and Selective Inhibitors of P38 Mitogen Activated Protein Kinase J.Med.Chem. V. 54 7899 2011.
Page generated: Sun Dec 13 11:51:05 2020
ISSN: ISSN 0022-2623 PubMed: 21999461 DOI: 10.1021/JM200975U |
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