Fluorine in PDB 3nvh: Mihfgnd Segment 137-143 From Mouse Prion

The structure of Mihfgnd Segment 137-143 From Mouse Prion, PDB code: 3nvh was solved by M.I.Apostol, M.R.Sawaya, D.Eisenberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.70 / 1.61
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	30.280, 4.873, 31.107, 90.00, 90.00, 90.00
R / Rfree (%)	16.6 / 19.7

The binding sites of Fluorine atom in the Mihfgnd Segment 137-143 From Mouse Prion (pdb code 3nvh). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Mihfgnd Segment 137-143 From Mouse Prion, PDB code: 3nvh:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Mihfgnd Segment 137-143 From Mouse Prion


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Mihfgnd Segment 137-143 From Mouse Prion within 5.0Å range: probe atom residue distance (Å) B Occ A:F8 b:34.6 occ:1.00 F1 A:TFA8 0.0 34.6 1.0 C2 A:TFA8 1.3 32.7 1.0 F2 A:TFA8 2.1 32.4 1.0 F3 A:TFA8 2.2 33.2 1.0 C1 A:TFA8 2.3 32.5 1.0 OXT A:TFA8 2.9 31.6 1.0 O A:TFA8 3.2 31.8 1.0 ND2 A:ASN6 4.8 9.6 1.0 OD1 A:ASN6 4.8 8.4 1.0

Fluorine binding site 2 out of 3 in the Mihfgnd Segment 137-143 From Mouse Prion


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Mihfgnd Segment 137-143 From Mouse Prion within 5.0Å range: probe atom residue distance (Å) B Occ A:F8 b:32.4 occ:1.00 F2 A:TFA8 0.0 32.4 1.0 C2 A:TFA8 1.3 32.7 1.0 F1 A:TFA8 2.1 34.6 1.0 F3 A:TFA8 2.1 33.2 1.0 C1 A:TFA8 2.4 32.5 1.0 OXT A:TFA8 2.8 31.6 1.0 O A:TFA8 3.3 31.8 1.0

Fluorine binding site 3 out of 3 in the Mihfgnd Segment 137-143 From Mouse Prion


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Mihfgnd Segment 137-143 From Mouse Prion within 5.0Å range: probe atom residue distance (Å) B Occ A:F8 b:33.2 occ:1.00 F3 A:TFA8 0.0 33.2 1.0 C2 A:TFA8 1.3 32.7 1.0 F2 A:TFA8 2.1 32.4 1.0 F1 A:TFA8 2.2 34.6 1.0 C1 A:TFA8 2.3 32.5 1.0 O A:TFA8 2.5 31.8 1.0 ND2 A:ASN6 3.1 9.6 1.0 OD1 A:ASN6 3.4 8.4 1.0 OXT A:TFA8 3.4 31.6 1.0 CG A:ASN6 3.6 7.5 1.0

M.I.Apostol, J.J.Wiltzius, M.R.Sawaya, D.Cascio, D.Eisenberg. Atomic Structures Suggest Determinants of Transmission Barriers in Mammalian Prion Disease. Biochemistry V. 50 2456 2011.
ISSN: ISSN 0006-2960
PubMed: 21323366
DOI: 10.1021/BI101803K