|
Atomistry » Fluorine » PDB 3nlz-3og7 » 3o6h | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3nlz-3og7 » 3o6h » |
Fluorine in PDB 3o6h: Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric ModulatorProtein crystallography data
The structure of Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator, PDB code: 3o6h
was solved by
J.K.F.Maclean,
R.A.Campbell,
I.A.Cumming,
K.J.Gillen,
J.Gillespie,
C.Jamieson,
B.Kazemier,
M.Kiczun,
Y.Lamont,
A.J.Lyons,
F.Martin,
E.M.Moir,
J.A.Morrow,
J.Pantling,
Z.Rankovic,
L.Smith,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
(pdb code 3o6h). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator, PDB code: 3o6h: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 3o6hGo back to Fluorine Binding Sites List in 3o6h
Fluorine binding site 1 out
of 3 in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 3o6hGo back to Fluorine Binding Sites List in 3o6h
Fluorine binding site 2 out
of 3 in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 3o6hGo back to Fluorine Binding Sites List in 3o6h
Fluorine binding site 3 out
of 3 in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
Mono view Stereo pair view
Reference:
C.Jamieson,
R.A.Campbell,
I.A.Cumming,
K.J.Gillen,
J.Gillespie,
B.Kazemier,
M.Kiczun,
Y.Lamont,
A.J.Lyons,
J.K.Maclean,
F.Martin,
E.M.Moir,
J.A.Morrow,
J.Pantling,
Z.Rankovic,
L.Smith.
A Novel Series of Positive Modulators of the Ampa Receptor: Structure-Based Lead Optimization. Bioorg.Med.Chem.Lett. V. 20 6072 2010.
Page generated: Sun Dec 13 11:52:10 2020
ISSN: ISSN 0960-894X PubMed: 20817521 DOI: 10.1016/J.BMCL.2010.08.063 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |