Fluorine in PDB 3oyf: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810, PDB code: 3oyf was solved by S.Hare, P.Cherepanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.65 / 2.51
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	159.340, 159.340, 123.260, 90.00, 90.00, 90.00
R / Rfree (%)	20.4 / 23.2

The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810 also contains other interesting chemical elements:

Magnesium	(Mg)	3 atoms
Zinc	(Zn)	1 atom

The binding sites of Fluorine atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810 (pdb code 3oyf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810, PDB code: 3oyf:

Fluorine binding site 1 out of 1 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti L-870,810 within 5.0Å range: probe atom residue distance (Å) B Occ A:F398 b:42.5 occ:1.00 FAE A:ZYP398 0.0 42.5 1.0 CAV A:ZYP398 1.3 39.3 1.0 CAI A:ZYP398 2.3 38.6 1.0 CAH A:ZYP398 2.4 37.5 1.0 N1 C:DG4 2.9 36.5 1.0 C6 C:DG4 3.0 37.6 1.0 O6 C:DG4 3.3 39.4 1.0 N4 D:DC16 3.3 29.9 1.0 N3 D:DC16 3.3 33.4 1.0 C4 D:DC16 3.4 32.5 1.0 C2 C:DG4 3.4 34.8 1.0 CAK A:ZYP398 3.6 38.4 1.0 CAJ A:ZYP398 3.6 39.0 1.0 C5 C:DG4 3.7 36.6 1.0 CG A:GLN215 3.8 45.2 1.0 CA A:GLN215 3.9 39.4 1.0 N A:GLN215 3.9 38.5 1.0 N2 C:DG4 4.0 32.4 1.0 N3 C:DG4 4.0 33.5 1.0 C4 C:DG4 4.1 36.3 1.0 CAW A:ZYP398 4.1 39.3 1.0 C2 D:DC16 4.1 31.9 1.0 C5 D:DC16 4.3 30.5 1.0 OE1 A:GLN215 4.3 50.7 1.0 CD A:GLN215 4.3 51.7 1.0 C A:PRO214 4.4 38.1 1.0 O C:HOH253 4.4 50.1 1.0 CB A:GLN215 4.4 40.5 1.0 O D:HOH328 4.5 57.2 1.0 O A:PRO214 4.6 38.6 1.0 O2 D:DC16 4.6 33.6 1.0 N7 C:DG4 4.6 35.8 1.0 CB A:PRO214 4.8 37.6 1.0 N1 D:DC16 4.8 31.4 1.0 C6 D:DC16 4.9 30.9 1.0

S.Hare, A.M.Vos, R.F.Clayton, J.W.Thuring, M.D.Cummings, P.Cherepanov. Molecular Mechanisms of Retroviral Integrase Inhibition and the Evolution of Viral Resistance. Proc.Natl.Acad.Sci.Usa V. 107 20057 2010.
ISSN: ISSN 0027-8424
PubMed: 21030679
DOI: 10.1073/PNAS.1010246107