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Atomistry » Fluorine » PDB 3oyl-3pr2 » 3p0p » |
Fluorine in PDB 3p0p: Human Tankyrase 2 - Catalytic Parp Domain in Complex with An InhibitorEnzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
All present enzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor:
2.4.2.30; Protein crystallography data
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0p
was solved by
T.Karlberg,
M.I.Siponen,
C.H.Arrowsmith,
H.Berglund,
C.Bountra,
R.Collins,
A.M.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
I.Johansson,
T.Kotenyova,
E.Kouznetsova,
M.Moche,
P.Nordlund,
T.Nyman,
C.Persson,
P.Schutz,
A.Sehic,
A.G.Thorsell,
L.Tresaugues,
S.Van Den Berg,
E.Wahlberg,
J.Weigelt,
M.Welin,
H.Schuler,
Structural Genomicsconsortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3p0p:
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
(pdb code 3p0p). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0p: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 3p0pGo back to Fluorine Binding Sites List in 3p0p
Fluorine binding site 1 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 3p0pGo back to Fluorine Binding Sites List in 3p0p
Fluorine binding site 2 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
E.Wahlberg,
T.Karlberg,
E.Kouznetsova,
N.Markova,
A.Macchiarulo,
A.G.Thorsell,
E.Pol,
A.Frostell,
T.Ekblad,
B.Kull,
G.M.Robertson,
R.Pellicciari,
H.Schuler,
J.Weigelt.
Family-Wide Chemical Profiling and Structural Analysis of Parp and Tankyrase Inhibitors Nat.Biotechnol. V. 30 283 2012.
Page generated: Sun Dec 13 11:52:57 2020
ISSN: ISSN 1087-0156 PubMed: 22343925 DOI: 10.1038/NBT.2121 |
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