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Atomistry » Fluorine » PDB 3oyl-3pr2 » 3pmw » |
Fluorine in PDB 3pmw: Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric ModulatorProtein crystallography data
The structure of Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator, PDB code: 3pmw
was solved by
J.K.F.Maclean,
C.Jamieson,
C.I.Brown,
R.A.Campbell,
K.J.Gillen,
J.Gillespie,
B.Kazemier,
M.Kiczun,
Y.Lamont,
A.J.Lyons,
E.M.Moir,
J.A.Morrow,
J.Pantling,
Z.Rankovic,
L.Smith,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
(pdb code 3pmw). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator, PDB code: 3pmw: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 3pmwGo back to Fluorine Binding Sites List in 3pmw
Fluorine binding site 1 out
of 3 in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 3pmwGo back to Fluorine Binding Sites List in 3pmw
Fluorine binding site 2 out
of 3 in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 3pmwGo back to Fluorine Binding Sites List in 3pmw
Fluorine binding site 3 out
of 3 in the Ligand-Binding Domain of GLUA2 (Flip) Ionotropic Glutamate Receptor in Complex with An Allosteric Modulator
Mono view Stereo pair view
Reference:
C.Jamieson,
J.K.Maclean,
C.I.Brown,
R.A.Campbell,
K.J.Gillen,
J.Gillespie,
B.Kazemier,
M.Kiczun,
Y.Lamont,
A.J.Lyons,
E.M.Moir,
J.A.Morrow,
J.Pantling,
Z.Rankovic,
L.Smith.
Structure Based Evolution of A Novel Series of Positive Modulators of the Ampa Receptor. Bioorg.Med.Chem.Lett. V. 21 805 2011.
Page generated: Sun Dec 13 11:53:13 2020
ISSN: ISSN 0960-894X PubMed: 21190850 DOI: 10.1016/J.BMCL.2010.11.098 |
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