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Atomistry » Fluorine » PDB 3qrj-3rgf » 3qtz » |
Fluorine in PDB 3qtz: CDK2 in Complex with Inhibitor Rc-2-36Enzymatic activity of CDK2 in Complex with Inhibitor Rc-2-36
All present enzymatic activity of CDK2 in Complex with Inhibitor Rc-2-36:
2.7.11.22; Protein crystallography data
The structure of CDK2 in Complex with Inhibitor Rc-2-36, PDB code: 3qtz
was solved by
S.Betzi,
R.Alam,
H.Han,
A.Becker,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the CDK2 in Complex with Inhibitor Rc-2-36
(pdb code 3qtz). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the CDK2 in Complex with Inhibitor Rc-2-36, PDB code: 3qtz: Fluorine binding site 1 out of 1 in 3qtzGo back to Fluorine Binding Sites List in 3qtz
Fluorine binding site 1 out
of 1 in the CDK2 in Complex with Inhibitor Rc-2-36
Mono view Stereo pair view
Reference:
E.Schonbrunn,
S.Betzi,
R.Alam,
M.P.Martin,
A.Becker,
H.Han,
R.Francis,
R.Chakrasali,
S.Jakkaraj,
A.Kazi,
S.M.Sebti,
C.L.Cubitt,
A.W.Gebhard,
L.A.Hazlehurst,
J.S.Tash,
G.I.Georg.
Development of Highly Potent and Selective Diaminothiazole Inhibitors of Cyclin-Dependent Kinases. J.Med.Chem. V. 56 3768 2013.
Page generated: Sun Dec 13 11:54:06 2020
ISSN: ISSN 0022-2623 PubMed: 23600925 DOI: 10.1021/JM301234K |
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