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Atomistry » Fluorine » PDB 3qrj-3rgf » 3qup » |
Fluorine in PDB 3qup: Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky)Enzymatic activity of Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky)
All present enzymatic activity of Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky):
2.7.10.1; Protein crystallography data
The structure of Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky), PDB code: 3qup
was solved by
J.F.Ohren,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky)
(pdb code 3qup). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky), PDB code: 3qup: Fluorine binding site 1 out of 1 in 3qupGo back to Fluorine Binding Sites List in 3qup
Fluorine binding site 1 out
of 1 in the Inhibitor Bound Structure of the Kinase Domain of the Murine Receptor Tyrosine Kinase TYRO3 (Sky)
Mono view Stereo pair view
Reference:
N.A.Powell,
J.T.Kohrt,
K.J.Filipski,
M.Kaufman,
D.Sheehan,
J.E.Edmunds,
A.Delaney,
Y.Wang,
F.Bourbonais,
D.Y.Lee,
F.Schwende,
F.Sun,
P.Mcconnell,
C.Catana,
H.Chen,
J.Ohren,
L.A.Perrin.
Novel and Selective Spiroindoline-Based Inhibitors of Sky Kinase. Bioorg.Med.Chem.Lett. V. 22 190 2012.
Page generated: Sun Dec 13 11:54:08 2020
ISSN: ISSN 0960-894X PubMed: 22119469 DOI: 10.1016/J.BMCL.2011.11.036 |
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