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Atomistry » Fluorine » PDB 3sb0-3sym » 3shy » |
Fluorine in PDB 3shy: Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel InhibitorsEnzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
All present enzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors:
3.1.4.35; Protein crystallography data
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 3shy
was solved by
T.T.Chen,
T.Chen,
Y.C.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3shy:
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
(pdb code 3shy). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 3shy: Fluorine binding site 1 out of 1 in 3shyGo back to Fluorine Binding Sites List in 3shy
Fluorine binding site 1 out
of 1 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
Mono view Stereo pair view
Reference:
Z.Xu,
Z.Liu,
T.Chen,
T.T.Chen,
Z.Wang,
G.Tian,
J.Shi,
X.Wang,
Y.Lu,
X.Yan,
G.Wang,
H.Jiang,
K.Chen,
S.Wang,
Y.Xu,
J.Shen,
W.Zhu.
Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem. V. 54 5607 2011.
Page generated: Sun Dec 13 11:55:13 2020
ISSN: ISSN 0022-2623 PubMed: 21714539 DOI: 10.1021/JM200644R |
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