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Fluorine in PDB 3u2o: Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule InhibitorEnzymatic activity of Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule Inhibitor
All present enzymatic activity of Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule Inhibitor:
1.3.5.2; Protein crystallography data
The structure of Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule Inhibitor, PDB code: 3u2o
was solved by
E.Lozoya,
V.Segarra,
M.Erra,
C.Wenzkowski,
A.Jestel,
S.Krapp,
M.Blaesse,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule Inhibitor
(pdb code 3u2o). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule Inhibitor, PDB code: 3u2o: Fluorine binding site 1 out of 1 in 3u2oGo back to Fluorine Binding Sites List in 3u2o
Fluorine binding site 1 out
of 1 in the Dihydroorotate Dehydrogenase (Dhodh) Crystal Structure in Complex with Small Molecule Inhibitor
Mono view Stereo pair view
Reference:
M.Erra,
I.Moreno,
J.Sanahuja,
M.Andres,
R.F.Reinoso,
E.Lozoya,
P.Pizcueta,
N.Godessart,
J.C.Castro-Palomino.
Biaryl Analogues of Teriflunomide As Potent Dhodh Inhibitors. Bioorg.Med.Chem.Lett. V. 21 7268 2011.
Page generated: Sun Dec 13 11:56:10 2020
ISSN: ISSN 0960-894X PubMed: 22078215 DOI: 10.1016/J.BMCL.2011.10.052 |
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