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Atomistry » Fluorine » PDB 3u5k-3uxm » 3uph | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3u5k-3uxm » 3uph » |
Fluorine in PDB 3uph: Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase InhibitorsEnzymatic activity of Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors
All present enzymatic activity of Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors:
2.7.7.48; Protein crystallography data
The structure of Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors, PDB code: 3uph
was solved by
F.Velazquez,
S.Venkataraman,
C.A.Lesburg,
J.S.Duca,
S.B.Rosenblum,
J.A.Kozlowski,
F.G.Njoroge,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors
(pdb code 3uph). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors, PDB code: 3uph: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 3uphGo back to Fluorine Binding Sites List in 3uph
Fluorine binding site 1 out
of 4 in the Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 3uphGo back to Fluorine Binding Sites List in 3uph
Fluorine binding site 2 out
of 4 in the Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 3uphGo back to Fluorine Binding Sites List in 3uph
Fluorine binding site 3 out
of 4 in the Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 3uphGo back to Fluorine Binding Sites List in 3uph
Fluorine binding site 4 out
of 4 in the Synthesis of Novel 4,5-Dihydrofurano Indoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors
Mono view Stereo pair view
Reference:
F.Velazquez,
S.Venkatraman,
C.A.Lesburg,
J.Duca,
S.B.Rosenblum,
J.A.Kozlowski,
F.G.Njoroge.
Synthesis of New 4,5-Dihydrofuranoindoles and Their Evaluation As Hcv NS5B Polymerase Inhibitors. Org.Lett. V. 14 556 2012.
Page generated: Wed Jul 31 23:06:06 2024
ISSN: ISSN 1523-7060 PubMed: 22220815 DOI: 10.1021/OL203177G |
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