Atomistry » Fluorine » PDB 3wyl-460d » 3zsh
Atomistry »
  Fluorine »
    PDB 3wyl-460d »
      3zsh »

Fluorine in PDB 3zsh: X-Ray Structure of P38ALPHA Bound to Scio-469

Enzymatic activity of X-Ray Structure of P38ALPHA Bound to Scio-469

All present enzymatic activity of X-Ray Structure of P38ALPHA Bound to Scio-469:
2.7.11.24;

Protein crystallography data

The structure of X-Ray Structure of P38ALPHA Bound to Scio-469, PDB code: 3zsh was solved by R.Azevedo, M.Van Zeeland, H.Raaijmakers, B.Kazemier, A.Oubrie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.15 / 2.05
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.720, 70.080, 74.290, 90.00, 90.00, 90.00
R / Rfree (%) 20.5 / 25.5

Other elements in 3zsh:

The structure of X-Ray Structure of P38ALPHA Bound to Scio-469 also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the X-Ray Structure of P38ALPHA Bound to Scio-469 (pdb code 3zsh). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the X-Ray Structure of P38ALPHA Bound to Scio-469, PDB code: 3zsh:

Fluorine binding site 1 out of 1 in 3zsh

Go back to Fluorine Binding Sites List in 3zsh
Fluorine binding site 1 out of 1 in the X-Ray Structure of P38ALPHA Bound to Scio-469


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of X-Ray Structure of P38ALPHA Bound to Scio-469 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F400

b:42.5
occ:1.00
FAI A:469400 0.0 42.5 1.0
CAX A:469400 1.3 41.0 1.0
CAK A:469400 2.3 41.1 1.0
CAL A:469400 2.4 40.2 1.0
CB A:LEU104 3.1 35.2 1.0
CAM A:469400 3.6 41.8 1.0
C A:LEU104 3.6 35.5 1.0
CAN A:469400 3.6 40.2 1.0
N A:VAL105 3.7 34.7 1.0
CD1 A:LEU86 3.7 41.8 1.0
C A:VAL105 3.8 35.2 1.0
CB A:THR106 3.9 34.9 1.0
O A:LEU104 3.9 36.0 1.0
CA A:LEU104 4.0 35.3 1.0
N A:THR106 4.0 35.9 1.0
CD1 A:LEU75 4.0 40.9 1.0
O A:VAL105 4.0 35.3 1.0
CAZ A:469400 4.1 39.9 1.0
CA A:VAL105 4.2 34.8 1.0
CG2 A:THR106 4.2 34.2 1.0
CG A:LEU104 4.3 34.1 1.0
CD1 A:LEU104 4.3 34.5 1.0
CA A:THR106 4.5 35.0 1.0
CB A:LYS53 4.9 37.6 0.5
CG A:LEU86 4.9 41.3 1.0
CB A:LYS53 4.9 37.5 0.5
O A:GLY85 4.9 38.3 1.0
O A:ALA51 5.0 35.5 1.0
OG1 A:THR106 5.0 33.3 1.0

Reference:

R.Azevedo, M.Van Zeeland, H.Raaijmakers, B.Kazemier, J.De Vlieg, A.Oubrie. X-Ray Structure of P38 Alpha Bound to Tak-715: Comparison with Three Classic Inhibitors. Acta Crystallogr. D Biol. V. 68 1041 2012CRYSTALLOGR..
ISSN: ESSN 1399-0047
PubMed: 22868770
DOI: 10.1107/S090744491201997X
Page generated: Sun Dec 13 11:58:19 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy