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Fluorine in PDB 4b3o: Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface
Enzymatic activity of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface
All present enzymatic activity of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface:
2.7.7.49; 2.7.7.7; 3.1.13.2; 3.1.26.13; 3.4.23.16;
2.7.7.49; 2.7.7.7; 3.1.13.2; 3.1.26.13; 3.4.23.16;
Protein crystallography data
The structure of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface, PDB code: 4b3o
was solved by
M.Lapkouski,
L.Tian,
J.T.Miller,
S.F.J.Le Grice,
W.Yang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.73 / 3.30 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 164.598, 164.598, 129.030, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 27.5 / 29.5 |
Other elements in 4b3o:
The structure of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface also contains other interesting chemical elements:
| Calcium | (Ca) | 2 atoms |
| Chlorine | (Cl) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface
(pdb code 4b3o). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface, PDB code: 4b3o:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface, PDB code: 4b3o:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 4b3o
Go back to
Fluorine Binding Sites List in 4b3o
Fluorine binding site 1 out
of 3 in the Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 4b3o
Go back to
Fluorine Binding Sites List in 4b3o
Fluorine binding site 2 out
of 3 in the Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 4b3o
Go back to
Fluorine Binding Sites List in 4b3o
Fluorine binding site 3 out
of 3 in the Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Structures of Hiv-1 Rt and Rna-Dna Complex Reveal A Unique Rt Conformation and Substrate Interface within 5.0Å range:
|
Reference:
M.Lapkouski,
L.Tian,
J.T.Miller,
S.F.J.Le Grice,
W.Yang.
Complexes of Hiv-1 Rt, Nnrti and Rna/Dna Hybrid Reveal A Structure Compatible with Rna Degradation Nat.Struct.Mol.Biol. V. 20 230 2013.
ISSN: ISSN 1545-9993
PubMed: 23314251
DOI: 10.1038/NSMB.2485
Page generated: Sun Dec 13 11:59:05 2020
ISSN: ISSN 1545-9993
PubMed: 23314251
DOI: 10.1038/NSMB.2485
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