Atomistry » Fluorine » PDB 4csj-4dbq » 4d7h
Atomistry »
  Fluorine »
    PDB 4csj-4dbq »
      4d7h »

Fluorine in PDB 4d7h: Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine

Enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine

All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine:
1.14.13.165;

Protein crystallography data

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine, PDB code: 4d7h was solved by J.K.Holden, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.62 / 2.02
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.870, 94.670, 62.837, 90.00, 90.00, 90.00
R / Rfree (%) 18.5 / 23.8

Other elements in 4d7h:

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine also contains other interesting chemical elements:

Iron (Fe) 1 atom
Chlorine (Cl) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine (pdb code 4d7h). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine, PDB code: 4d7h:

Fluorine binding site 1 out of 1 in 4d7h

Go back to Fluorine Binding Sites List in 4d7h
Fluorine binding site 1 out of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 7-(2-(3-(3-Fluorophenyl(Propylamino)Ethyl))Quinolin-2- Amine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F904

b:96.2
occ:1.00
 F23 A:M46904 0.0 96.2 1.0
C23 A:M46904 1.3 95.4 1.0
C22 A:M46904 2.4 91.0 1.0
C24 A:M46904 2.4 97.4 1.0
C21 A:M46904 3.6 86.2 1.0
C25 A:M46904 3.6 96.1 1.0
C26 A:M46904 4.1 91.5 1.0
O A:HOH2062 4.6 54.6 1.0
O A:HOH2059 4.8 45.1 1.0
C16 A:M46904 4.9 75.8 1.0

Reference:

J.K.Holden, S.Kang, F.C.Beasley, M.A.Cinelli, H.Li, S.G.Roy, D.Dejam, A.L.Edinger, V.Nizet, R.B.Silverman, T.L.Poulos. Nitric Oxide Synthase As A Target For Methicillin-Resistant Staphylococcus Aureus Chem.Biol. V. 22 785 2015.
ISSN: ISSN 1074-5521
PubMed: 26091171
DOI: 10.1016/J.CHEMBIOL.2015.05.013
Page generated: Sun Dec 13 12:01:05 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy