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Fluorine in PDB 4d7i: Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine
Enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine
All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine:
1.14.13.165;
1.14.13.165;
Protein crystallography data
The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine, PDB code: 4d7i
was solved by
J.K.Holden,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 48.94 / 1.96 |
| Space group | P 21 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 80.560, 95.050, 61.620, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 18.9 / 23.5 |
Other elements in 4d7i:
The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine also contains other interesting chemical elements:
| Iron | (Fe) | 1 atom |
| Chlorine | (Cl) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine
(pdb code 4d7i). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine, PDB code: 4d7i:
In total only one binding site of Fluorine was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine, PDB code: 4d7i:
Fluorine binding site 1 out of 1 in 4d7i
Go back to
Fluorine Binding Sites List in 4d7i
Fluorine binding site 1 out
of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 6-(4-(((3-Fluorophenethyl)Amino)Methyl)Phenyl)-4-Methylpyridin- 2- Amine within 5.0Å range:
|
Reference:
J.K.Holden,
S.Kang,
F.C.Beasley,
M.A.Cinelli,
H.Li,
S.G.Roy,
D.Dejam,
A.L.Edinger,
V.Nizet,
R.B.Silverman,
T.L.Poulos.
Nitric Oxide Synthase As A Target For Methicillin-Resistant Staphylococcus Aureus Chem.Biol. V. 22 785 2015.
ISSN: ISSN 1074-5521
PubMed: 26091171
DOI: 10.1016/J.CHEMBIOL.2015.05.013
Page generated: Thu Aug 1 00:52:36 2024
ISSN: ISSN 1074-5521
PubMed: 26091171
DOI: 10.1016/J.CHEMBIOL.2015.05.013
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