Fluorine in PDB 4dkj: Cpg Specific Methyltransferase in Complex with Target Dna

All present enzymatic activity of Cpg Specific Methyltransferase in Complex with Target Dna:
2.1.1.37;

The structure of Cpg Specific Methyltransferase in Complex with Target Dna, PDB code: 4dkj was solved by M.Wojciechowski, H.Czapinska, M.Bochtler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.60 / 2.15
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	83.950, 83.950, 173.840, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 21.6

The binding sites of Fluorine atom in the Cpg Specific Methyltransferase in Complex with Target Dna (pdb code 4dkj). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cpg Specific Methyltransferase in Complex with Target Dna, PDB code: 4dkj:

Fluorine binding site 1 out of 1 in the Cpg Specific Methyltransferase in Complex with Target Dna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cpg Specific Methyltransferase in Complex with Target Dna within 5.0Å range: probe atom residue distance (Å) B Occ B:F8 b:33.3 occ:1.00 F B:C378 0.0 33.3 1.0 C5 B:C378 1.4 26.5 1.0 C6 B:C378 2.4 22.3 1.0 C4 B:C378 2.4 26.8 1.0 N4 B:C378 2.7 26.2 1.0 N A:CYS135 3.0 24.4 1.0 O A:HOH664 3.2 19.6 0.5 CA A:PRO134 3.4 22.4 1.0 O A:PHE133 3.4 21.5 1.0 SD A:SAH501 3.4 28.1 0.7 C5' A:SAH501 3.5 26.9 0.7 C A:PRO134 3.6 23.5 1.0 N1 B:C378 3.6 18.5 1.0 N3 B:C378 3.6 21.3 1.0 CB A:CYS135 3.6 26.4 1.0 SG A:CYS135 3.7 31.4 1.0 CA A:CYS135 4.0 26.0 1.0 C A:PHE133 4.1 21.9 1.0 C2 B:C378 4.1 17.7 1.0 N A:PRO134 4.1 22.4 1.0 O A:HOH724 4.3 35.6 1.0 CB A:PRO134 4.5 23.4 1.0 O A:SER132 4.6 22.7 1.0 O A:PRO134 4.7 23.3 1.0 CG A:SAH501 4.7 22.4 0.7 OD1 A:ASN374 4.8 17.4 1.0 O A:HOH773 4.8 34.9 1.0 C1' B:C378 4.9 17.2 1.0 O A:ASN374 4.9 19.3 1.0 C4' A:SAH501 5.0 26.1 0.7

M.Wojciechowski, H.Czapinska, M.Bochtler. Cpg Underrepresentation and the Bacterial Cpg-Specific Dna Methyltransferase M.Mpei. Proc.Natl.Acad.Sci.Usa V. 110 105 2013.
ISSN: ISSN 0027-8424
PubMed: 23248272
DOI: 10.1073/PNAS.1207986110