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Atomistry » Fluorine » PDB 4f9w-4fvx » 4fjy » |
Fluorine in PDB 4fjy: Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24FEnzymatic activity of Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24F
All present enzymatic activity of Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24F:
2.7.1.153; 2.7.11.1; Protein crystallography data
The structure of Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24F, PDB code: 4fjy
was solved by
D.A.Whittington,
J.Tang,
P.Yakowec,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24F
(pdb code 4fjy). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24F, PDB code: 4fjy: Fluorine binding site 1 out of 1 in 4fjyGo back to Fluorine Binding Sites List in 4fjy
Fluorine binding site 1 out
of 1 in the Crystal Structure of PI3K-Gamma in Complex with Quinoline-Indoline Inhibitor 24F
Mono view Stereo pair view
Reference:
F.Gonzalez-Lopez De Turiso,
Y.Shin,
M.Brown,
M.Cardozo,
Y.Chen,
D.Fong,
X.Hao,
X.He,
K.Henne,
Y.L.Hu,
M.G.Johnson,
T.Kohn,
J.Lohman,
H.J.Mcbride,
L.R.Mcgee,
J.C.Medina,
D.Metz,
K.Miner,
D.Mohn,
V.Pattaropong,
J.Seganish,
J.L.Simard,
S.Wannberg,
D.A.Whittington,
G.Yu,
T.D.Cushing.
Discovery and in Vivo Evaluation of Dual PI3K-Beta/Delta Inhibitors J.Med.Chem. V. 55 7667 2012.
Page generated: Sun Dec 13 12:02:33 2020
ISSN: ISSN 0022-2623 PubMed: 22876881 DOI: 10.1021/JM300679U |
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