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Atomistry » Fluorine » PDB 4fxq-4goa » 4gg7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4fxq-4goa » 4gg7 » |
Fluorine in PDB 4gg7: Crystal Structure of Cmet in Complex with Novel InhibitorEnzymatic activity of Crystal Structure of Cmet in Complex with Novel Inhibitor
All present enzymatic activity of Crystal Structure of Cmet in Complex with Novel Inhibitor:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Cmet in Complex with Novel Inhibitor, PDB code: 4gg7
was solved by
Q.F.Liu,
T.T.Chen,
Y.C.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Cmet in Complex with Novel Inhibitor
(pdb code 4gg7). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Cmet in Complex with Novel Inhibitor, PDB code: 4gg7: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 4gg7Go back to Fluorine Binding Sites List in 4gg7
Fluorine binding site 1 out
of 3 in the Crystal Structure of Cmet in Complex with Novel Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 4gg7Go back to Fluorine Binding Sites List in 4gg7
Fluorine binding site 2 out
of 3 in the Crystal Structure of Cmet in Complex with Novel Inhibitor
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 4gg7Go back to Fluorine Binding Sites List in 4gg7
Fluorine binding site 3 out
of 3 in the Crystal Structure of Cmet in Complex with Novel Inhibitor
Mono view Stereo pair view
Reference:
K.Wu,
J.Ai,
Q.Liu,
T.Chen,
A.Zhao,
X.Peng,
Y.Wang,
Y.Ji,
Q.Yao,
Y.Xu,
M.Geng,
A.Zhang.
Multisubstituted Quinoxalines and Pyrido[2,3-D]Pyrimidines: Synthesis and Sar Study As Tyrosine Kinase C-Met Inhibitors. Bioorg.Med.Chem.Lett. V. 22 6368 2012.
Page generated: Sun Dec 13 12:03:16 2020
ISSN: ISSN 0960-894X PubMed: 22985853 DOI: 10.1016/J.BMCL.2012.08.075 |
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