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Atomistry » Fluorine » PDB 4gpb-4hw7 » 4hlh » |
Fluorine in PDB 4hlh: Crystal Structure of Tankyrase 2 in Complex with 4'-FluoroflavoneEnzymatic activity of Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone
All present enzymatic activity of Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone:
2.4.2.30; Protein crystallography data
The structure of Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone, PDB code: 4hlh
was solved by
M.Narwal,
T.Haikarainen,
L.Lehtio,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4hlh:
The structure of Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone
(pdb code 4hlh). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone, PDB code: 4hlh: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 4hlhGo back to Fluorine Binding Sites List in 4hlh
Fluorine binding site 1 out
of 2 in the Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 4hlhGo back to Fluorine Binding Sites List in 4hlh
Fluorine binding site 2 out
of 2 in the Crystal Structure of Tankyrase 2 in Complex with 4'-Fluoroflavone
Mono view Stereo pair view
Reference:
M.Narwal,
T.Haikarainen,
A.Fallarero,
P.M.Vuorela,
L.Lehtio.
Screening and Structural Analysis of Flavones Inhibiting Tankyrases. J.Med.Chem. V. 56 3507 2013.
Page generated: Sun Dec 13 12:03:48 2020
ISSN: ISSN 0022-2623 PubMed: 23574272 DOI: 10.1021/JM3018783 |
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