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Fluorine in PDB 4hu1: Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor., PDB code: 4hu1
was solved by
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 40.18 / 1.95 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 56.270, 57.386, 159.552, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.9 / 23.5 |
Other elements in 4hu1:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. also contains other interesting chemical elements:
| Zinc | (Zn) | 2 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
(pdb code 4hu1). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 8 binding sites of Fluorine where determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor., PDB code: 4hu1:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Fluorine where determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor., PDB code: 4hu1:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Fluorine binding site 1 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 1 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 2 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 2 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 3 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 3 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 4 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 4 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 5 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 5 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 6 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 6 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 7 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 7 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Fluorine binding site 8 out of 8 in 4hu1
Go back to
Fluorine Binding Sites List in 4hu1
Fluorine binding site 8 out
of 8 in the Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Crystal Structure of Human Carbonic Anhydrase Isozyme XIII with the Inhibitor. within 5.0Å range:
|
Reference:
V.Dudutiene,
A.Zubriene,
A.Smirnov,
J.Gylyte,
D.Timm,
E.Manakova,
S.Grazulis,
D.Matulis.
4-Substituted-2,3,5,6-Tetrafluorobenzenesulfonamides As Inhibitors of Carbonic Anhydrases I, II, VII, XII, and XIII. Bioorg.Med.Chem. V. 21 2093 2013.
ISSN: ISSN 0968-0896
PubMed: 23394791
DOI: 10.1016/J.BMC.2013.01.008
Page generated: Thu Aug 1 02:08:18 2024
ISSN: ISSN 0968-0896
PubMed: 23394791
DOI: 10.1016/J.BMC.2013.01.008
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