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Atomistry » Fluorine » PDB 4hxn-4ijh » 4ify | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4hxn-4ijh » 4ify » |
Fluorine in PDB 4ify: Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles SiteEnzymatic activity of Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site
All present enzymatic activity of Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site:
2.7.7.49; 2.7.7.7; 3.1.26.13; Protein crystallography data
The structure of Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site, PDB code: 4ify
was solved by
J.D.Bauman,
D.Patel,
E.Arnold,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ify:
The structure of Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site
(pdb code 4ify). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site, PDB code: 4ify: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 4ifyGo back to Fluorine Binding Sites List in 4ify
Fluorine binding site 1 out
of 3 in the Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 4ifyGo back to Fluorine Binding Sites List in 4ify
Fluorine binding site 2 out
of 3 in the Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 4ifyGo back to Fluorine Binding Sites List in 4ify
Fluorine binding site 3 out
of 3 in the Hiv-1 Reverse Transcriptase with Bound Fragment at the Knuckles Site
Mono view Stereo pair view
Reference:
J.D.Bauman,
D.Patel,
C.Dharia,
M.W.Fromer,
S.Ahmed,
Y.Frenkel,
R.S.Vijayan,
J.T.Eck,
W.C.Ho,
K.Das,
A.J.Shatkin,
E.Arnold.
Detecting Allosteric Sites of Hiv-1 Reverse Transcriptase By X-Ray Crystallographic Fragment Screening. J.Med.Chem. V. 56 2738 2013.
Page generated: Thu Aug 1 02:25:29 2024
ISSN: ISSN 0022-2623 PubMed: 23342998 DOI: 10.1021/JM301271J |
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