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Atomistry » Fluorine » PDB 4hxn-4ijh » 4igh » |
Fluorine in PDB 4igh: High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid AnalogEnzymatic activity of High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid Analog
All present enzymatic activity of High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid Analog:
1.3.5.2; Protein crystallography data
The structure of High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid Analog, PDB code: 4igh
was solved by
X.Deng,
P.Das,
B.M.A.Fontoura,
M.A.Phillips,
J.K.De Brabander,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid Analog
(pdb code 4igh). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid Analog, PDB code: 4igh: Fluorine binding site 1 out of 1 in 4ighGo back to Fluorine Binding Sites List in 4igh
Fluorine binding site 1 out
of 1 in the High Resolution Crystal Structure of Human Dihydroorotate Dehydrogenase Bound with 4-Quinoline Carboxylic Acid Analog
Mono view Stereo pair view
Reference:
P.Das,
X.Deng,
L.Zhang,
M.G.Roth,
B.M.Fontoura,
M.A.Phillips,
J.K.De Brabander.
Sar Based Optimization of A 4-Quinoline Carboxylic Acid Analog with Potent Anti-Viral Activity. Acs Med.Chem.Lett. V. 4 517 2013.
Page generated: Sun Dec 13 12:04:31 2020
ISSN: ISSN 1948-5875 PubMed: 23930152 DOI: 10.1021/ML300464H |
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