Fluorine in PDB 4iw8: Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A

The structure of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A, PDB code: 4iw8 was solved by J.C.Nwachukwu, S.Srinivasan, A.A.Parent, V.Cavett, J.Nowak, T.S.Hughes, D.J.Kojetin, J.A.Katzenellenbogen, K.W.Nettles, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.73 / 2.04
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	54.170, 81.094, 58.119, 90.00, 109.49, 90.00
R / Rfree (%)	20.8 / 24.7

The binding sites of Fluorine atom in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A (pdb code 4iw8). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 9 binding sites of Fluorine where determined in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A, PDB code: 4iw8:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Fluorine binding site 1 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:48.0 occ:1.00 FAX A:KN3601 0.0 48.0 1.0 CAW A:KN3601 1.4 49.3 1.0 HAKA A:KN3601 2.1 56.4 1.0 FAY A:KN3601 2.3 51.9 1.0 FAZ A:KN3601 2.3 48.4 1.0 CAF A:KN3601 2.4 37.0 1.0 CAK A:KN3601 3.0 47.0 1.0 CAE A:KN3601 3.1 33.9 1.0 CA A:GLY521 3.3 41.1 1.0 NAI A:KN3601 3.3 40.9 1.0 O A:GLY521 3.5 36.4 1.0 CAA A:KN3601 3.6 46.5 1.0 HAL A:KN3601 3.7 91.7 1.0 C A:GLY521 3.7 39.3 1.0 CAL A:KN3601 3.7 76.5 1.0 HAK A:KN3601 3.7 56.4 1.0 HAA A:KN3601 3.8 55.7 1.0 CAD A:KN3601 4.4 40.1 1.0 CB A:HIS524 4.5 51.0 1.0 CE A:MET388 4.6 32.7 1.0 N A:GLY521 4.6 41.4 1.0 CD2 A:LEU384 4.6 32.6 1.0 CD1 A:ILE424 4.6 58.6 1.0 NAH A:KN3601 4.7 43.3 1.0 SD A:MET421 4.8 0.1 1.0 CAB A:KN3601 4.8 47.1 1.0 N A:MET522 4.9 40.4 1.0 CE A:MET421 4.9 0.1 1.0

Fluorine binding site 2 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:51.9 occ:1.00 FAY A:KN3601 0.0 51.9 1.0 CAW A:KN3601 1.4 49.3 1.0 FAX A:KN3601 2.3 48.0 1.0 FAZ A:KN3601 2.3 48.4 1.0 HAA A:KN3601 2.4 55.7 1.0 CAF A:KN3601 2.4 37.0 1.0 CAA A:KN3601 2.7 46.5 1.0 O A:GLY521 3.3 36.4 1.0 N A:LEU525 3.6 39.0 1.0 CA A:LEU525 3.8 44.7 1.0 CAE A:KN3601 3.8 33.9 1.0 CB A:LEU525 3.8 43.8 1.0 CB A:HIS524 4.0 51.0 1.0 HAKA A:KN3601 4.1 56.4 1.0 C A:HIS524 4.2 39.4 1.0 SD A:MET528 4.2 56.7 1.0 C A:GLY521 4.2 39.3 1.0 CAB A:KN3601 4.2 47.1 1.0 CD1 A:LEU525 4.4 49.6 1.0 HAL A:KN3601 4.5 91.7 1.0 CE A:MET343 4.5 42.0 1.0 CA A:GLY521 4.5 41.1 1.0 CA A:HIS524 4.7 43.4 1.0 NAI A:KN3601 4.7 40.9 1.0 CG A:LEU525 4.7 49.5 1.0 CAK A:KN3601 4.7 47.0 1.0 O A:HIS524 4.8 42.8 1.0 HAB A:KN3601 4.8 56.4 1.0 CE A:MET421 4.9 0.1 1.0 CAD A:KN3601 5.0 40.1 1.0 CE A:MET528 5.0 52.7 1.0

Fluorine binding site 3 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ A:F601 b:48.4 occ:1.00 FAZ A:KN3601 0.0 48.4 1.0 CAW A:KN3601 1.4 49.3 1.0 HAL A:KN3601 2.2 91.7 1.0 FAY A:KN3601 2.3 51.9 1.0 FAX A:KN3601 2.3 48.0 1.0 CAF A:KN3601 2.4 37.0 1.0 HAKA A:KN3601 2.8 56.4 1.0 CAL A:KN3601 2.9 76.5 1.0 CAK A:KN3601 3.1 47.0 1.0 CE A:MET343 3.2 42.0 1.0 CAE A:KN3601 3.2 33.9 1.0 NAI A:KN3601 3.5 40.9 1.0 CAA A:KN3601 3.5 46.5 1.0 SD A:MET421 3.6 0.1 1.0 CE A:MET421 3.7 0.1 1.0 HAA A:KN3601 3.7 55.7 1.0 HAK A:KN3601 4.1 56.4 1.0 SD A:MET343 4.2 71.1 1.0 CAM A:KN3601 4.3 75.6 1.0 CAD A:KN3601 4.5 40.1 1.0 HANA A:KN3601 4.7 84.1 1.0 CB A:HIS524 4.7 51.0 1.0 SD A:MET528 4.7 56.7 1.0 CAB A:KN3601 4.8 47.1 1.0 NAH A:KN3601 4.8 43.3 1.0 HANB A:KN3601 4.9 84.1 1.0 CAN A:KN3601 4.9 70.2 1.0

Fluorine binding site 4 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ B:F601 b:47.0 occ:0.46 FAX B:KN3601 0.0 47.0 0.5 CAW B:KN3601 1.4 48.5 0.5 FAZ B:KN3601 2.1 48.5 0.5 HAKA B:KN3601 2.2 50.3 0.5 FAY B:KN3601 2.3 47.5 0.5 FAZ B:KN3601 2.3 49.5 0.5 FAX B:KN3601 2.3 48.3 0.5 HAA B:KN3601 2.4 51.3 0.5 CAF B:KN3601 2.4 41.8 0.5 CAW B:KN3601 2.7 46.6 0.5 CAA B:KN3601 2.8 42.9 0.5 CAK B:KN3601 3.1 42.0 0.5 CAL B:KN3601 3.3 44.2 0.5 FAY B:KN3601 3.3 44.7 0.5 CD1 B:ILE424 3.4 47.1 0.7 HAL B:KN3601 3.6 52.9 0.5 ND1 B:HIS524 3.6 51.1 0.7 HAK B:KN3601 3.7 50.3 0.5 HAOA B:KN3601 3.7 0.7 0.5 CB B:HIS524 3.8 40.8 0.7 CAE B:KN3601 3.8 41.5 0.5 CG B:HIS524 3.9 48.8 0.7 CAF B:KN3601 4.0 43.5 0.5 CAM B:KN3601 4.1 44.7 0.5 N B:MET421 4.1 96.9 0.8 HAK B:KN3601 4.2 51.8 0.5 NAI B:KN3601 4.2 41.2 0.5 CAB B:KN3601 4.2 41.8 0.5 CA B:GLY521 4.3 28.6 0.8 CAO B:KN3601 4.3 1.0 0.5 HAKA B:KN3601 4.4 51.8 0.5 CAE B:KN3601 4.5 41.6 0.5 CE1 B:HIS524 4.5 53.2 0.7 O B:GLY420 4.5 1.0 1.0 O B:GLY521 4.5 30.2 0.8 CG1 B:ILE424 4.5 45.8 0.7 CAK B:KN3601 4.6 43.2 0.5 CB B:MET421 4.6 95.4 1.0 CB B:ILE424 4.6 41.3 0.7 NAI B:KN3601 4.6 42.4 0.5 HAO B:KN3601 4.7 0.7 0.5 C B:GLY420 4.7 0.5 1.0 CG2 B:ILE424 4.7 41.6 0.7 CD2 B:HIS524 4.8 53.8 0.7 HAB B:KN3601 4.8 50.0 0.5 CE B:MET343 4.9 64.9 0.8 C B:GLY521 4.9 30.7 0.8 CAD B:KN3601 5.0 40.3 0.5 CA B:MET421 5.0 92.2 0.7

Fluorine binding site 5 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ B:F601 b:48.3 occ:0.54 FAX B:KN3601 0.0 48.3 0.5 FAY B:KN3601 0.6 47.5 0.5 CAW B:KN3601 1.4 46.6 0.5 CAW B:KN3601 1.5 48.5 0.5 HAKA B:KN3601 2.1 50.3 0.5 CAF B:KN3601 2.2 41.8 0.5 FAY B:KN3601 2.3 44.7 0.5 FAZ B:KN3601 2.3 48.5 0.5 FAX B:KN3601 2.3 47.0 0.5 HAKA B:KN3601 2.3 51.8 0.5 CAF B:KN3601 2.4 43.5 0.5 FAZ B:KN3601 2.7 49.5 0.5 CAE B:KN3601 2.8 41.5 0.5 CAK B:KN3601 2.9 43.2 0.5 HAK B:KN3601 2.9 51.8 0.5 CAK B:KN3601 3.1 42.0 0.5 O B:GLY521 3.1 30.2 0.8 NAI B:KN3601 3.1 42.4 0.5 CAE B:KN3601 3.1 41.6 0.5 CA B:GLY521 3.2 28.6 0.8 CAA B:KN3601 3.3 42.9 0.5 NAI B:KN3601 3.4 41.2 0.5 C B:GLY521 3.5 30.7 0.8 CAA B:KN3601 3.5 43.5 0.5 HAK B:KN3601 3.6 50.3 0.5 HAA B:KN3601 3.7 51.3 0.5 HAA B:KN3601 3.7 52.1 0.5 CAL B:KN3601 4.1 44.2 0.5 CAD B:KN3601 4.1 40.3 0.5 HAL B:KN3601 4.3 52.9 0.5 CAL B:KN3601 4.4 44.6 0.5 NAH B:KN3601 4.4 41.9 0.5 CB B:HIS524 4.4 40.8 0.7 CAD B:KN3601 4.5 41.5 0.5 CD1 B:ILE424 4.5 47.1 0.7 CAB B:KN3601 4.5 41.8 0.5 N B:LEU525 4.6 34.6 0.8 N B:GLY521 4.6 31.2 0.8 CE B:MET388 4.6 20.4 0.8 N B:MET522 4.7 27.7 0.9 HANB B:KN3601 4.7 0.5 0.5 NAH B:KN3601 4.8 40.9 0.5 CD2 B:LEU384 4.8 19.3 0.7 CAB B:KN3601 4.8 44.5 0.5 CAC B:KN3601 4.8 40.4 0.5 HAL B:KN3601 4.9 53.4 0.5 ND1 B:HIS524 4.9 51.1 0.7 CAG B:KN3601 4.9 40.0 0.5 CB B:LEU525 4.9 36.2 0.8

Fluorine binding site 6 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ B:F601 b:47.5 occ:0.46 FAY B:KN3601 0.0 47.5 0.5 FAX B:KN3601 0.6 48.3 0.5 CAW B:KN3601 1.0 46.6 0.5 CAW B:KN3601 1.4 48.5 0.5 FAY B:KN3601 1.7 44.7 0.5 FAZ B:KN3601 2.0 48.5 0.5 HAKA B:KN3601 2.2 51.8 0.5 FAX B:KN3601 2.3 47.0 0.5 FAZ B:KN3601 2.3 49.5 0.5 CAF B:KN3601 2.3 43.5 0.5 CAF B:KN3601 2.4 41.8 0.5 HAKA B:KN3601 2.5 50.3 0.5 HAK B:KN3601 2.6 51.8 0.5 CAK B:KN3601 2.7 43.2 0.5 O B:GLY521 3.0 30.2 0.8 CAE B:KN3601 3.0 41.5 0.5 NAI B:KN3601 3.1 42.4 0.5 CAE B:KN3601 3.3 41.6 0.5 CAA B:KN3601 3.3 43.5 0.5 CAK B:KN3601 3.4 42.0 0.5 HAA B:KN3601 3.4 52.1 0.5 CA B:GLY521 3.5 28.6 0.8 C B:GLY521 3.6 30.7 0.8 CAA B:KN3601 3.6 42.9 0.5 NAI B:KN3601 3.7 41.2 0.5 HAA B:KN3601 3.9 51.3 0.5 HAK B:KN3601 4.1 50.3 0.5 CB B:HIS524 4.1 40.8 0.7 N B:LEU525 4.1 34.6 0.8 CAL B:KN3601 4.2 44.6 0.5 CAL B:KN3601 4.2 44.2 0.5 HAL B:KN3601 4.4 52.9 0.5 CAD B:KN3601 4.4 40.3 0.5 HANB B:KN3601 4.4 0.5 0.5 ND1 B:HIS524 4.4 51.1 0.7 NAH B:KN3601 4.5 41.9 0.5 CB B:LEU525 4.6 36.2 0.8 CAD B:KN3601 4.6 41.5 0.5 CG B:HIS524 4.7 48.8 0.7 CA B:LEU525 4.7 37.4 0.8 CAB B:KN3601 4.7 44.5 0.5 C B:HIS524 4.7 35.8 0.7 CD1 B:ILE424 4.7 47.1 0.7 HAL B:KN3601 4.7 53.4 0.5 CAB B:KN3601 4.9 41.8 0.5 HAN B:KN3601 4.9 0.5 0.5 N B:MET522 4.9 27.7 0.9 CA B:HIS524 4.9 33.3 0.7 N B:GLY521 4.9 31.2 0.8 CAN B:KN3601 5.0 0.5 0.5

Fluorine binding site 7 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ B:F601 b:44.7 occ:0.54 FAY B:KN3601 0.0 44.7 0.5 CAW B:KN3601 1.4 46.6 0.5 FAY B:KN3601 1.7 47.5 0.5 HAK B:KN3601 1.8 51.8 0.5 HAKA B:KN3601 2.1 51.8 0.5 FAZ B:KN3601 2.2 49.5 0.5 FAX B:KN3601 2.3 48.3 0.5 FAZ B:KN3601 2.3 48.5 0.5 CAK B:KN3601 2.4 43.2 0.5 HAA B:KN3601 2.4 52.1 0.5 CAW B:KN3601 2.4 48.5 0.5 CAF B:KN3601 2.4 43.5 0.5 CAA B:KN3601 2.7 43.5 0.5 N B:LEU525 3.3 34.6 0.8 FAX B:KN3601 3.3 47.0 0.5 O B:GLY521 3.4 30.2 0.8 CA B:LEU525 3.4 37.4 0.8 CAL B:KN3601 3.4 44.6 0.5 HAN B:KN3601 3.4 0.5 0.5 NAI B:KN3601 3.5 42.4 0.5 HANB B:KN3601 3.5 0.5 0.5 CB B:LEU525 3.5 36.2 0.8 CAF B:KN3601 3.6 41.8 0.5 SD B:MET528 3.7 0.2 0.9 CAN B:KN3601 3.8 0.5 0.5 CAE B:KN3601 3.8 41.6 0.5 CAE B:KN3601 3.8 41.5 0.5 C B:HIS524 3.9 35.8 0.7 HAKA B:KN3601 3.9 50.3 0.5 ND1 B:HIS524 3.9 51.1 0.7 CAM B:KN3601 4.1 42.9 0.5 CB B:HIS524 4.1 40.8 0.7 HAL B:KN3601 4.2 53.4 0.5 CD1 B:LEU525 4.2 40.0 0.8 CAB B:KN3601 4.2 44.5 0.5 O B:HIS524 4.4 39.1 0.7 C B:GLY521 4.4 30.7 0.8 CG B:LEU525 4.5 38.5 0.8 CG B:HIS524 4.5 48.8 0.7 CA B:HIS524 4.6 33.3 0.7 CAK B:KN3601 4.7 42.0 0.5 NAI B:KN3601 4.7 41.2 0.5 CA B:GLY521 4.8 28.6 0.8 HANA B:KN3601 4.8 0.5 0.5 HAB B:KN3601 4.8 53.3 0.5 NAH B:KN3601 4.8 41.9 0.5 CG B:MET528 4.8 61.9 0.9 SD B:MET343 4.9 83.5 0.8 C B:LEU525 4.9 43.1 0.8 CAA B:KN3601 4.9 42.9 0.5 CAD B:KN3601 5.0 41.5 0.5 CE B:MET343 5.0 64.9 0.8

Fluorine binding site 8 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ B:F601 b:49.5 occ:0.46 FAZ B:KN3601 0.0 49.5 0.5 FAZ B:KN3601 0.6 48.5 0.5 CAW B:KN3601 1.4 48.5 0.5 CAW B:KN3601 1.7 46.6 0.5 FAY B:KN3601 2.2 44.7 0.5 FAX B:KN3601 2.3 47.0 0.5 FAY B:KN3601 2.3 47.5 0.5 CAF B:KN3601 2.4 41.8 0.5 HAK B:KN3601 2.4 51.8 0.5 FAX B:KN3601 2.7 48.3 0.5 CAF B:KN3601 2.8 43.5 0.5 HAKA B:KN3601 2.9 50.3 0.5 HAL B:KN3601 3.1 52.9 0.5 CAE B:KN3601 3.2 41.5 0.5 CAK B:KN3601 3.2 43.2 0.5 HANB B:KN3601 3.3 0.5 0.5 HAKA B:KN3601 3.4 51.8 0.5 CAL B:KN3601 3.4 44.2 0.5 CAA B:KN3601 3.5 42.9 0.5 CAK B:KN3601 3.5 42.0 0.5 CE B:MET343 3.5 64.9 0.8 NAI B:KN3601 3.5 42.4 0.5 CAE B:KN3601 3.6 41.6 0.5 ND1 B:HIS524 3.6 51.1 0.7 HAA B:KN3601 3.6 51.3 0.5 SD B:MET343 3.7 83.5 0.8 CAA B:KN3601 3.8 43.5 0.5 HAA B:KN3601 3.8 52.1 0.5 NAI B:KN3601 3.9 41.2 0.5 HAN B:KN3601 4.0 0.5 0.5 SD B:MET528 4.1 0.2 0.9 CAN B:KN3601 4.1 0.5 0.5 CE1 B:HIS524 4.4 53.2 0.7 HAK B:KN3601 4.4 50.3 0.5 O B:GLY420 4.4 1.0 1.0 CG B:HIS524 4.5 48.8 0.7 CAD B:KN3601 4.5 40.3 0.5 CAL B:KN3601 4.6 44.6 0.5 CB B:HIS524 4.6 40.8 0.7 CAM B:KN3601 4.7 44.7 0.5 CD1 B:LEU346 4.7 49.6 0.8 CAB B:KN3601 4.7 41.8 0.5 HANA B:KN3601 4.8 0.5 0.5 CAM B:KN3601 4.9 42.9 0.5 CAD B:KN3601 4.9 41.5 0.5 NAH B:KN3601 4.9 41.9 0.5 O B:GLY521 5.0 30.2 0.8

Fluorine binding site 9 out of 9 in the Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Crystal Structure of the Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Dynamic Way-Derivative, 9A within 5.0Å range: probe atom residue distance (Å) B Occ B:F601 b:48.5 occ:0.54 FAZ B:KN3601 0.0 48.5 0.5 FAZ B:KN3601 0.6 49.5 0.5 CAW B:KN3601 1.0 48.5 0.5 CAW B:KN3601 1.4 46.6 0.5 CAF B:KN3601 1.9 41.8 0.5 FAY B:KN3601 2.0 47.5 0.5 FAX B:KN3601 2.1 47.0 0.5 FAY B:KN3601 2.3 44.7 0.5 FAX B:KN3601 2.3 48.3 0.5 HAK B:KN3601 2.3 51.8 0.5 HAKA B:KN3601 2.4 50.3 0.5 CAF B:KN3601 2.4 43.5 0.5 CAE B:KN3601 2.7 41.5 0.5 HAL B:KN3601 2.8 52.9 0.5 CAK B:KN3601 2.9 42.0 0.5 CAA B:KN3601 3.0 42.9 0.5 CAK B:KN3601 3.0 43.2 0.5 CAL B:KN3601 3.0 44.2 0.5 CAE B:KN3601 3.1 41.6 0.5 NAI B:KN3601 3.1 42.4 0.5 HAKA B:KN3601 3.2 51.8 0.5 HAA B:KN3601 3.3 51.3 0.5 NAI B:KN3601 3.3 41.2 0.5 HANB B:KN3601 3.4 0.5 0.5 CAA B:KN3601 3.6 43.5 0.5 HAA B:KN3601 3.8 52.1 0.5 HAK B:KN3601 3.9 50.3 0.5 CE B:MET343 4.0 64.9 0.8 CAD B:KN3601 4.0 40.3 0.5 ND1 B:HIS524 4.0 51.1 0.7 SD B:MET343 4.1 83.5 0.8 HAN B:KN3601 4.2 0.5 0.5 CAN B:KN3601 4.2 0.5 0.5 CAB B:KN3601 4.2 41.8 0.5 CAM B:KN3601 4.4 44.7 0.5 CAL B:KN3601 4.4 44.6 0.5 CAD B:KN3601 4.4 41.5 0.5 NAH B:KN3601 4.5 41.9 0.5 SD B:MET528 4.5 0.2 0.9 CD1 B:LEU346 4.6 49.6 0.8 O B:GLY420 4.6 1.0 1.0 CAC B:KN3601 4.6 40.4 0.5 NAH B:KN3601 4.7 40.9 0.5 CG B:HIS524 4.8 48.8 0.7 CAB B:KN3601 4.8 44.5 0.5 CE1 B:HIS524 4.8 53.2 0.7 CB B:HIS524 4.8 40.8 0.7 CAM B:KN3601 4.8 42.9 0.5 O B:GLY521 4.9 30.2 0.8 CAG B:KN3601 4.9 40.0 0.5 HAOA B:KN3601 4.9 0.7 0.5 HANA B:KN3601 5.0 0.5 0.5

S.Srinivasan, J.C.Nwachukwu, A.A.Parent, V.Cavett, J.Nowak, T.S.Hughes, D.J.Kojetin, J.A.Katzenellenbogen, K.W.Nettles. Ligand Binding Dynamics Rewire Cellular Signaling Via Estrogen Receptor-Alpha Nat.Chem.Biol. V. 9 326 2013.
ISSN: ISSN 1552-4450
PubMed: 23524984
DOI: 10.1038/NCHEMBIO.1214