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Atomistry » Fluorine » PDB 4iju-4j0t » 4j03 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4iju-4j0t » 4j03 » |
Fluorine in PDB 4j03: Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with FulvestrantEnzymatic activity of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
All present enzymatic activity of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant:
3.1.3.76; 3.3.2.10; Protein crystallography data
The structure of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant, PDB code: 4j03
was solved by
C.Morisseau,
S.Pakhomova,
S.H.Hwang,
M.E.Newcomer,
B.D.Hammock,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4j03:
The structure of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
(pdb code 4j03). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 5 binding sites of Fluorine where determined in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant, PDB code: 4j03: Jump to Fluorine binding site number: 1; 2; 3; 4; 5; Fluorine binding site 1 out of 5 in 4j03Go back to Fluorine Binding Sites List in 4j03
Fluorine binding site 1 out
of 5 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
Mono view Stereo pair view
Fluorine binding site 2 out of 5 in 4j03Go back to Fluorine Binding Sites List in 4j03
Fluorine binding site 2 out
of 5 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
Mono view Stereo pair view
Fluorine binding site 3 out of 5 in 4j03Go back to Fluorine Binding Sites List in 4j03
Fluorine binding site 3 out
of 5 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
Mono view Stereo pair view
Fluorine binding site 4 out of 5 in 4j03Go back to Fluorine Binding Sites List in 4j03
Fluorine binding site 4 out
of 5 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
Mono view Stereo pair view
Fluorine binding site 5 out of 5 in 4j03Go back to Fluorine Binding Sites List in 4j03
Fluorine binding site 5 out
of 5 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with Fulvestrant
Mono view Stereo pair view
Reference:
C.Morisseau,
S.Pakhomova,
S.H.Hwang,
M.E.Newcomer,
B.D.Hammock.
Inhibition of Soluble Epoxide Hydrolase By Fulvestrant and Sulfoxides. Bioorg.Med.Chem.Lett. V. 23 3818 2013.
Page generated: Sun Dec 13 12:05:00 2020
ISSN: ISSN 0960-894X PubMed: 23684894 DOI: 10.1016/J.BMCL.2013.04.083 |
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