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Atomistry » Fluorine » PDB 4lvt-4mm8 » 4lwu » |
Fluorine in PDB 4lwu: The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252Protein crystallography data
The structure of The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252, PDB code: 4lwu
was solved by
B.J.Graves,
C.Lukacs,
C.A.Janson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4lwu:
The structure of The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252
(pdb code 4lwu). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252, PDB code: 4lwu: Fluorine binding site 1 out of 1 in 4lwuGo back to Fluorine Binding Sites List in 4lwu
Fluorine binding site 1 out
of 1 in the The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252
Mono view Stereo pair view
Reference:
Z.Zhang,
Q.Ding,
J.J.Liu,
J.Zhang,
N.Jiang,
X.J.Chu,
D.Bartkovitz,
K.C.Luk,
C.Janson,
C.Tovar,
Z.M.Filipovic,
B.Higgins,
K.Glenn,
K.Packman,
L.T.Vassilev,
B.Graves.
Discovery of Potent and Selective Spiroindolinone MDM2 Inhibitor, RO8994, For Cancer Therapy. Bioorg.Med.Chem. V. 22 4001 2014.
Page generated: Sun Dec 13 12:07:19 2020
ISSN: ISSN 0968-0896 PubMed: 24997575 DOI: 10.1016/J.BMC.2014.05.072 |
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