|
Atomistry » Fluorine » PDB 4lvt-4mm8 » 4m4q | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4lvt-4mm8 » 4m4q » |
Fluorine in PDB 4m4q: 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 EndonucleaseProtein crystallography data
The structure of 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease, PDB code: 4m4q
was solved by
J.D.Bauman,
D.Patel,
K.Das,
E.Arnold,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4m4q:
The structure of 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease
(pdb code 4m4q). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease, PDB code: 4m4q: Fluorine binding site 1 out of 1 in 4m4qGo back to Fluorine Binding Sites List in 4m4q
Fluorine binding site 1 out
of 1 in the 6-(4-Fluorophenyl)-3-Hydroxy-5-[4-(1H-1,2,3,4-Tetrazol-5-Yl)Phenyl] - 1,2-Dihydropyridin-2-One Bound to Influenza 2009 H1N1 Endonuclease
Mono view Stereo pair view
Reference:
J.D.Bauman,
D.Patel,
S.F.Baker,
R.S.Vijayan,
A.Xiang,
A.K.Parhi,
L.Martinez-Sobrido,
E.J.Lavoie,
K.Das,
E.Arnold.
Crystallographic Fragment Screening and Structure-Based Optimization Yields A New Class of Influenza Endonuclease Inhibitors. Acs Chem.Biol. V. 8 2501 2013.
Page generated: Sun Dec 13 12:07:38 2020
ISSN: ISSN 1554-8929 PubMed: 23978130 DOI: 10.1021/CB400400J |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |