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Atomistry » Fluorine » PDB 4mm9-4ncg » 4n98 » |
Fluorine in PDB 4n98: E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic AcidEnzymatic activity of E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid
All present enzymatic activity of E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid:
2.7.7.7; Protein crystallography data
The structure of E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid, PDB code: 4n98
was solved by
Z.Yin,
A.J.Oakley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4n98:
The structure of E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid
(pdb code 4n98). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid, PDB code: 4n98: Fluorine binding site 1 out of 1 in 4n98Go back to Fluorine Binding Sites List in 4n98
Fluorine binding site 1 out
of 1 in the E. Coli Sliding Clamp in Complex with 4'-Fluorobiphenyl-4-Carboxylic Acid
Mono view Stereo pair view
Reference:
Z.Yin,
L.R.Whittell,
Y.Wang,
S.Jergic,
M.Liu,
E.J.Harry,
N.E.Dixon,
J.L.Beck,
M.J.Kelso,
A.J.Oakley.
Discovery of Lead Compounds Targeting the Bacterial Sliding Clamp Using A Fragment-Based Approach. J.Med.Chem. V. 57 2799 2014.
Page generated: Sun Dec 13 12:08:44 2020
ISSN: ISSN 0022-2623 PubMed: 24592885 DOI: 10.1021/JM500122R |
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