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Atomistry » Fluorine » PDB 4ncj-4o16 » 4ncm » |
Fluorine in PDB 4ncm: Influenza Polymerase Basic Protein 2 (PB2) Bound to A Small-Molecule InhibitorProtein crystallography data
The structure of Influenza Polymerase Basic Protein 2 (PB2) Bound to A Small-Molecule Inhibitor, PDB code: 4ncm
was solved by
M.D.Jacobs,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ncm:
The structure of Influenza Polymerase Basic Protein 2 (PB2) Bound to A Small-Molecule Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Influenza Polymerase Basic Protein 2 (PB2) Bound to A Small-Molecule Inhibitor
(pdb code 4ncm). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Influenza Polymerase Basic Protein 2 (PB2) Bound to A Small-Molecule Inhibitor, PDB code: 4ncm: Fluorine binding site 1 out of 1 in 4ncmGo back to Fluorine Binding Sites List in 4ncm
Fluorine binding site 1 out
of 1 in the Influenza Polymerase Basic Protein 2 (PB2) Bound to A Small-Molecule Inhibitor
Mono view Stereo pair view
Reference:
M.P.Clark,
M.W.Ledeboer,
I.Davies,
R.A.Byrn,
S.M.Jones,
E.Perola,
A.Tsai,
M.Jacobs,
K.Nti-Addae,
U.K.Bandarage,
M.J.Boyd,
R.S.Bethiel,
J.J.Court,
H.Deng,
J.P.Duffy,
W.A.Dorsch,
L.J.Farmer,
H.Gao,
W.Gu,
K.Jackson,
D.H.Jacobs,
J.M.Kennedy,
B.Ledford,
J.Liang,
F.Maltais,
M.Murcko,
T.Wang,
M.W.Wannamaker,
H.B.Bennett,
J.R.Leeman,
C.Mcneil,
W.P.Taylor,
C.Memmott,
M.Jiang,
R.Rijnbrand,
C.Bral,
U.Germann,
A.Nezami,
Y.Zhang,
F.G.Salituro,
Y.L.Bennani,
P.S.Charifson.
Discovery of A Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (Vx-787) of Influenza PB2. J.Med.Chem. V. 57 6668 2014.
Page generated: Sun Dec 13 12:08:51 2020
ISSN: ISSN 0022-2623 PubMed: 25019388 DOI: 10.1021/JM5007275 |
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