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Atomistry » Fluorine » PDB 4o28-4olh » 4ode » |
Fluorine in PDB 4ode: Co-Crystal Structure of MDM2 with Inhibitor Compound 4Protein crystallography data
The structure of Co-Crystal Structure of MDM2 with Inhibitor Compound 4, PDB code: 4ode
was solved by
P.L.Shaffer,
X.Huang,
P.Yakowec,
A.M.Long,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ode:
The structure of Co-Crystal Structure of MDM2 with Inhibitor Compound 4 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Co-Crystal Structure of MDM2 with Inhibitor Compound 4
(pdb code 4ode). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Co-Crystal Structure of MDM2 with Inhibitor Compound 4, PDB code: 4ode: Fluorine binding site 1 out of 1 in 4odeGo back to Fluorine Binding Sites List in 4ode
Fluorine binding site 1 out
of 1 in the Co-Crystal Structure of MDM2 with Inhibitor Compound 4
Mono view Stereo pair view
Reference:
A.Z.Gonzalez,
Z.Li,
H.P.Beck,
J.Canon,
A.Chen,
D.Chow,
J.Duquette,
J.Eksterowicz,
B.M.Fox,
J.Fu,
X.Huang,
J.Houze,
L.Jin,
Y.Li,
Y.Ling,
M.C.Lo,
A.M.Long,
L.R.Mcgee,
J.Mcintosh,
J.D.Oliner,
T.Osgood,
Y.Rew,
A.Y.Saiki,
P.Shaffer,
S.Wortman,
P.Yakowec,
X.Yan,
Q.Ye,
D.Yu,
X.Zhao,
J.Zhou,
S.H.Olson,
D.Sun,
J.C.Medina.
Novel Inhibitors of the MDM2-P53 Interaction Featuring Hydrogen Bond Acceptors As Carboxylic Acid Isosteres. J.Med.Chem. V. 57 2963 2014.
Page generated: Thu Aug 1 04:31:08 2024
ISSN: ISSN 0022-2623 PubMed: 24601644 DOI: 10.1021/JM401911V |
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