Fluorine in PDB 4pb2: Structure of Vccnt-7C8C Bound to 5-Fluorouridine

The structure of Structure of Vccnt-7C8C Bound to 5-Fluorouridine, PDB code: 4pb2 was solved by Z.L.Johnson, S.-Y.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.21 / 2.30
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	119.772, 119.772, 83.214, 90.00, 90.00, 120.00
R / Rfree (%)	20 / 21.6

The structure of Structure of Vccnt-7C8C Bound to 5-Fluorouridine also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Fluorine atom in the Structure of Vccnt-7C8C Bound to 5-Fluorouridine (pdb code 4pb2). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Vccnt-7C8C Bound to 5-Fluorouridine, PDB code: 4pb2:

Fluorine binding site 1 out of 1 in the Structure of Vccnt-7C8C Bound to 5-Fluorouridine


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of Vccnt-7C8C Bound to 5-Fluorouridine within 5.0Å range: probe atom residue distance (Å) B Occ A:F501 b:37.8 occ:1.00 F5 A:5UD501 0.0 37.8 1.0 C5 A:5UD501 1.3 41.8 1.0 C6 A:5UD501 2.3 40.8 1.0 C4 A:5UD501 2.4 38.9 1.0 O4 A:5UD501 2.7 48.1 1.0 CG1 A:VAL188 3.1 48.7 1.0 N1 A:5UD501 3.6 40.9 1.0 N3 A:5UD501 3.6 41.9 1.0 CZ A:PHE366 3.6 37.2 1.0 CD1 A:LEU259 3.7 39.4 1.0 CD2 A:LEU259 3.7 39.6 1.0 CG2 A:VAL188 3.9 47.8 1.0 C2 A:5UD501 4.1 42.1 1.0 CB A:VAL188 4.1 48.2 1.0 CE2 A:PHE366 4.2 36.3 1.0 CG A:LEU259 4.3 43.8 1.0 CB A:ALA185 4.4 35.5 1.0 O5' A:5UD501 4.5 41.7 1.0 CE1 A:PHE366 4.5 39.5 1.0 C1' A:5UD501 4.8 43.2 1.0 O4' A:5UD501 4.8 39.8 1.0 N A:VAL188 4.9 48.3 1.0

Z.L.Johnson, J.H.Lee, K.Lee, M.Lee, D.Y.Kwon, J.Hong, S.Y.Lee. Structural Basis of Nucleoside and Nucleoside Drug Selectivity By Concentrative Nucleoside Transporters. Elife V. 3 03604 2014.
ISSN: ESSN 2050-084X
PubMed: 25082345
DOI: 10.7554/ELIFE.03604