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Atomistry » Fluorine » PDB 4pb2-4q0d » 4q06 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4pb2-4q0d » 4q06 » |
Fluorine in PDB 4q06: Crystal Structure of Chimeric Carbonic Anhydrase IX with InhibitorEnzymatic activity of Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor
All present enzymatic activity of Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor, PDB code: 4q06
was solved by
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4q06:
The structure of Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor
(pdb code 4q06). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor, PDB code: 4q06: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 4q06Go back to![]() ![]()
Fluorine binding site 1 out
of 3 in the Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 3 in 4q06Go back to![]() ![]()
Fluorine binding site 2 out
of 3 in the Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor
![]() Mono view ![]() Stereo pair view
Fluorine binding site 3 out of 3 in 4q06Go back to![]() ![]()
Fluorine binding site 3 out
of 3 in the Crystal Structure of Chimeric Carbonic Anhydrase IX with Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
V.Dudutiene,
J.Matuliene,
A.Smirnov,
D.D.Timm,
A.Zubriene,
L.Baranauskiene,
V.Morkunaite,
J.Smirnoviene,
V.Michailoviene,
V.Juozapaitiene,
A.Mickeviciute,
J.Kazokaite,
S.Baksyte,
A.Kasiliauskaite,
J.Jachno,
J.Revuckiene,
M.Kisonaite,
V.Pilipuityte,
E.Ivanauskaite,
G.Milinaviciute,
V.Smirnovas,
V.Petrikaite,
V.Kairys,
V.Petrauskas,
P.Norvaisas,
D.Linge,
P.Gibieza,
E.Capkauskaite,
A.Zaksauskas,
E.Kazlauskas,
E.Manakova,
S.Grazulis,
J.E.Ladbury,
D.Matulis.
Discovery and Characterization of Novel Selective Inhibitors of Carbonic Anhydrase IX. J.Med.Chem. V. 57 9435 2014.
Page generated: Thu Aug 1 05:00:43 2024
ISSN: ISSN 0022-2623 PubMed: 25358084 DOI: 10.1021/JM501003K |
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