Fluorine in PDB 4tn6: CK1D in Complex with Inhibitor

All present enzymatic activity of CK1D in Complex with Inhibitor:
2.7.11.1; 2.7.11.26;

The structure of CK1D in Complex with Inhibitor, PDB code: 4tn6 was solved by S.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.63 / 2.41
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.487, 115.336, 61.533, 90.00, 109.27, 90.00
R / Rfree (%)	18.7 / 23.9

The binding sites of Fluorine atom in the CK1D in Complex with Inhibitor (pdb code 4tn6). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the CK1D in Complex with Inhibitor, PDB code: 4tn6:

Fluorine binding site 1 out of 1 in the CK1D in Complex with Inhibitor


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CK1D in Complex with Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:F401 b:42.6 occ:1.00 F1 A:PFO401 0.0 42.6 1.0 C3 A:PFO401 1.4 40.2 1.0 C4 A:PFO401 2.3 38.8 1.0 C2 A:PFO401 2.3 39.5 1.0 CB A:MET82 3.4 37.7 1.0 CG A:MET80 3.4 42.8 1.0 C A:MET80 3.4 35.8 1.0 O A:MET80 3.4 34.3 1.0 CB A:MET80 3.6 38.4 1.0 N A:MET82 3.6 34.7 1.0 C5 A:PFO401 3.6 40.0 1.0 C1 A:PFO401 3.6 36.7 1.0 CE A:MET80 3.7 42.3 1.0 N A:VAL81 3.7 31.1 1.0 CD1 A:ILE68 3.7 42.2 1.0 C A:VAL81 3.8 35.7 1.0 CA A:VAL81 4.0 29.4 1.0 CB A:LYS38 4.1 34.9 1.0 CE A:MET82 4.1 42.5 1.0 CA A:MET80 4.1 36.0 1.0 C6 A:PFO401 4.1 37.9 1.0 CA A:MET82 4.1 35.4 1.0 O A:ALA36 4.2 34.6 1.0 O A:VAL81 4.3 35.0 1.0 SD A:MET80 4.3 47.3 1.0 N A:LYS38 4.4 36.1 1.0 CG A:MET82 4.4 42.0 1.0 SD A:MET82 4.7 45.6 1.0 CA A:LYS38 4.9 35.0 1.0

S.Liu, S.Liu. N/A N/A.