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Atomistry » Fluorine » PDB 4u80-4uwf » 4ugl » |
Fluorine in PDB 4ugl: Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-DiamineEnzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine
All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine:
1.14.13.165; Protein crystallography data
The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine, PDB code: 4ugl
was solved by
J.K.Holden,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ugl:
The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine
(pdb code 4ugl). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine, PDB code: 4ugl: Fluorine binding site 1 out of 1 in 4uglGo back to Fluorine Binding Sites List in 4ugl
Fluorine binding site 1 out
of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with N1-(3-(2-(6-Amino-4-Methylpyridin-2-Yl)Ethyl)-5-Fluorophenyl)-N1- Cyclopropyl-N2-Methylethane-1,2-Diamine
Mono view Stereo pair view
Reference:
J.K.Holden,
D.Dejam,
M.C.Lewis,
H.Huang,
S.Kang,
Q.Jing,
F.Xue,
R.B.Silverman,
T.L.Poulos.
Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase. Biochemistry V. 54 4075 2015.
Page generated: Sun Dec 13 12:13:15 2020
ISSN: ISSN 0006-2960 PubMed: 26062720 DOI: 10.1021/ACS.BIOCHEM.5B00431 |
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