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Atomistry » Fluorine » PDB 4whr-4x7i » 4wua | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4whr-4x7i » 4wua » |
Fluorine in PDB 4wua: Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340Enzymatic activity of Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340
All present enzymatic activity of Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340, PDB code: 4wua
was solved by
M.Hoshina,
T.Ikura,
T.Hosoya,
M.Hagiwara,
N.Ito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340
(pdb code 4wua). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340, PDB code: 4wua: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 4wuaGo back to Fluorine Binding Sites List in 4wua
Fluorine binding site 1 out
of 3 in the Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 4wuaGo back to Fluorine Binding Sites List in 4wua
Fluorine binding site 2 out
of 3 in the Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 4wuaGo back to Fluorine Binding Sites List in 4wua
Fluorine binding site 3 out
of 3 in the Crystal Structure of Human SRPK1 Complexed to An Inhibitor SRPIN340
Mono view Stereo pair view
Reference:
S.Morooka,
M.Hoshina,
I.Kii,
T.Okabe,
H.Kojima,
N.Inoue,
Y.Okuno,
M.Denawa,
S.Yoshida,
J.Fukuhara,
K.Ninomiya,
T.Ikura,
T.Furuya,
T.Nagano,
K.Noda,
S.Ishida,
T.Hosoya,
N.Ito,
N.Yoshimura,
M.Hagiwara.
Identification of A Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice Mol.Pharmacol. V. 88 316 2015.
Page generated: Thu Aug 1 06:32:59 2024
ISSN: ESSN 1521-0111 PubMed: 25993998 DOI: 10.1124/MOL.114.097345 |
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