Fluorine in PDB 4xq0: Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride
Enzymatic activity of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride
All present enzymatic activity of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride:
3.1.3.16;
Protein crystallography data
The structure of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride, PDB code: 4xq0
was solved by
A.Ghosh,
C.D.Lima,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
36.60 /
1.85
|
Space group
|
P 21 21 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
55.422,
80.255,
89.196,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
15.8 /
20.1
|
Other elements in 4xq0:
The structure of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride
(pdb code 4xq0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the
Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride, PDB code: 4xq0:
Jump to Fluorine binding site number:
1;
2;
3;
Fluorine binding site 1 out
of 3 in 4xq0
Go back to
Fluorine Binding Sites List in 4xq0
Fluorine binding site 1 out
of 3 in the Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F170
b:16.7
occ:1.00
|
F1
|
A:BFD170
|
0.0
|
16.7
|
1.0
|
BE
|
A:BFD170
|
1.4
|
30.4
|
1.0
|
OD1
|
A:BFD170
|
2.3
|
14.0
|
1.0
|
F3
|
A:BFD170
|
2.3
|
14.5
|
1.0
|
F2
|
A:BFD170
|
2.4
|
16.0
|
1.0
|
O
|
A:HOH771
|
2.8
|
22.7
|
1.0
|
NZ
|
A:LYS280
|
2.9
|
16.6
|
1.0
|
O
|
A:HOH864
|
3.0
|
22.4
|
1.0
|
N
|
A:MET244
|
3.0
|
16.6
|
1.0
|
CE
|
A:LYS280
|
3.5
|
13.2
|
1.0
|
CA
|
A:THR243
|
3.5
|
14.0
|
1.0
|
CG
|
A:BFD170
|
3.5
|
12.1
|
1.0
|
O
|
A:HOH762
|
3.7
|
16.2
|
1.0
|
C
|
A:THR243
|
3.7
|
17.5
|
1.0
|
OG1
|
A:THR243
|
3.7
|
16.0
|
1.0
|
CB
|
A:MET244
|
3.8
|
18.5
|
1.0
|
MG
|
A:MG606
|
4.0
|
16.1
|
1.0
|
CA
|
A:MET244
|
4.0
|
14.6
|
1.0
|
O
|
A:HOH772
|
4.0
|
38.9
|
1.0
|
CG
|
A:MET244
|
4.0
|
24.6
|
1.0
|
O
|
A:TYR242
|
4.1
|
15.0
|
1.0
|
OD2
|
A:BFD170
|
4.1
|
15.2
|
1.0
|
CB
|
A:THR243
|
4.2
|
13.2
|
1.0
|
N
|
A:THR243
|
4.6
|
16.4
|
1.0
|
CB
|
A:BFD170
|
4.7
|
11.9
|
1.0
|
C
|
A:TYR242
|
4.8
|
13.5
|
1.0
|
N
|
A:LEU171
|
4.8
|
14.2
|
1.0
|
O
|
A:THR243
|
4.8
|
15.2
|
1.0
|
OD2
|
A:ASP297
|
4.9
|
15.6
|
1.0
|
N
|
A:ASP172
|
4.9
|
14.6
|
1.0
|
N
|
A:GLY245
|
4.9
|
17.2
|
1.0
|
CD
|
A:LYS280
|
5.0
|
15.3
|
1.0
|
O
|
A:HOH763
|
5.0
|
14.7
|
1.0
|
C
|
A:MET244
|
5.0
|
17.6
|
1.0
|
|
Fluorine binding site 2 out
of 3 in 4xq0
Go back to
Fluorine Binding Sites List in 4xq0
Fluorine binding site 2 out
of 3 in the Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F170
b:16.0
occ:1.00
|
F2
|
A:BFD170
|
0.0
|
16.0
|
1.0
|
BE
|
A:BFD170
|
1.4
|
30.4
|
1.0
|
MG
|
A:MG606
|
1.9
|
16.1
|
1.0
|
F3
|
A:BFD170
|
2.3
|
14.5
|
1.0
|
F1
|
A:BFD170
|
2.4
|
16.7
|
1.0
|
OD1
|
A:BFD170
|
2.4
|
14.0
|
1.0
|
OD2
|
A:BFD170
|
2.7
|
15.2
|
1.0
|
O
|
A:HOH762
|
2.8
|
16.2
|
1.0
|
CG
|
A:BFD170
|
2.9
|
12.1
|
1.0
|
O
|
A:ASP172
|
3.0
|
13.7
|
1.0
|
O
|
A:HOH763
|
3.0
|
14.7
|
1.0
|
O
|
A:HOH864
|
3.1
|
22.4
|
1.0
|
CB
|
A:ASP172
|
3.3
|
16.0
|
1.0
|
N
|
A:ASP172
|
3.3
|
14.6
|
1.0
|
O
|
A:HOH771
|
3.5
|
22.7
|
1.0
|
CA
|
A:ASP172
|
3.6
|
11.6
|
1.0
|
C
|
A:ASP172
|
3.7
|
11.8
|
1.0
|
O
|
A:HOH772
|
3.7
|
38.9
|
1.0
|
OD1
|
A:ASP298
|
4.0
|
14.1
|
1.0
|
OD2
|
A:ASP323
|
4.1
|
36.8
|
1.0
|
OD2
|
A:ASP172
|
4.3
|
22.6
|
1.0
|
C
|
A:LEU171
|
4.3
|
14.0
|
1.0
|
CG
|
A:ASP172
|
4.3
|
24.0
|
1.0
|
N
|
A:LEU171
|
4.4
|
14.2
|
1.0
|
CB
|
A:BFD170
|
4.4
|
11.9
|
1.0
|
NZ
|
A:LYS280
|
4.5
|
16.6
|
1.0
|
OG1
|
A:THR243
|
4.7
|
16.0
|
1.0
|
CA
|
A:LEU171
|
4.9
|
12.6
|
1.0
|
CG
|
A:ASP323
|
4.9
|
36.6
|
1.0
|
OD1
|
A:ASP297
|
4.9
|
17.9
|
1.0
|
OD1
|
A:ASP323
|
5.0
|
29.4
|
1.0
|
|
Fluorine binding site 3 out
of 3 in 4xq0
Go back to
Fluorine Binding Sites List in 4xq0
Fluorine binding site 3 out
of 3 in the Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Structure of Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1- R271A Bound to Beryllium Fluoride within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F170
b:14.5
occ:1.00
|
F3
|
A:BFD170
|
0.0
|
14.5
|
1.0
|
BE
|
A:BFD170
|
1.4
|
30.4
|
1.0
|
OD1
|
A:BFD170
|
2.3
|
14.0
|
1.0
|
F1
|
A:BFD170
|
2.3
|
16.7
|
1.0
|
F2
|
A:BFD170
|
2.3
|
16.0
|
1.0
|
OG1
|
A:THR243
|
2.7
|
16.0
|
1.0
|
N
|
A:ASP172
|
2.9
|
14.6
|
1.0
|
O
|
A:HOH864
|
3.0
|
22.4
|
1.0
|
N
|
A:LEU171
|
3.1
|
14.2
|
1.0
|
CG
|
A:BFD170
|
3.3
|
12.1
|
1.0
|
CB
|
A:THR243
|
3.3
|
13.2
|
1.0
|
CB
|
A:LEU171
|
3.5
|
11.3
|
1.0
|
CA
|
A:THR243
|
3.5
|
14.0
|
1.0
|
CA
|
A:LEU171
|
3.6
|
12.6
|
1.0
|
OD2
|
A:ASP172
|
3.6
|
22.6
|
1.0
|
C
|
A:LEU171
|
3.7
|
14.0
|
1.0
|
CB
|
A:ASP172
|
3.8
|
16.0
|
1.0
|
OD2
|
A:BFD170
|
3.8
|
15.2
|
1.0
|
CA
|
A:ASP172
|
3.9
|
11.6
|
1.0
|
N
|
A:MET244
|
4.0
|
16.6
|
1.0
|
CG
|
A:ASP172
|
4.0
|
24.0
|
1.0
|
MG
|
A:MG606
|
4.0
|
16.1
|
1.0
|
C
|
A:BFD170
|
4.2
|
11.1
|
1.0
|
C
|
A:THR243
|
4.3
|
17.5
|
1.0
|
O
|
A:TYR242
|
4.4
|
15.0
|
1.0
|
CG
|
A:LEU171
|
4.4
|
13.4
|
1.0
|
CA
|
A:BFD170
|
4.4
|
11.7
|
1.0
|
NZ
|
A:LYS280
|
4.5
|
16.6
|
1.0
|
CB
|
A:BFD170
|
4.5
|
11.9
|
1.0
|
O
|
A:ASP172
|
4.5
|
13.7
|
1.0
|
N
|
A:THR243
|
4.7
|
16.4
|
1.0
|
C
|
A:ASP172
|
4.7
|
11.8
|
1.0
|
CG2
|
A:THR243
|
4.7
|
17.0
|
1.0
|
O
|
A:HOH762
|
4.8
|
16.2
|
1.0
|
O
|
A:LEU171
|
4.8
|
15.6
|
1.0
|
O
|
A:HOH771
|
4.9
|
22.7
|
1.0
|
C
|
A:TYR242
|
5.0
|
13.5
|
1.0
|
N
|
A:GLY245
|
5.0
|
17.2
|
1.0
|
CD1
|
A:LEU171
|
5.0
|
14.9
|
1.0
|
|
Reference:
B.Schwer,
A.Ghosh,
A.M.Sanchez,
C.D.Lima,
S.Shuman.
Genetic and Structural Analysis of the Essential Fission Yeast Rna Polymerase II Ctd Phosphatase FCP1. Rna.
ISSN: ESSN 1469-9001
Page generated: Thu Aug 1 06:43:59 2024
|