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Atomistry » Fluorine » PDB 4xyf-4ymo » 4yd0 » |
Fluorine in PDB 4yd0: Influenza Polymerase Basic Protein 2 (PB2) Bound to An Azaindole- Tetrazole InhibitorProtein crystallography data
The structure of Influenza Polymerase Basic Protein 2 (PB2) Bound to An Azaindole- Tetrazole Inhibitor, PDB code: 4yd0
was solved by
M.D.Jacobs,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4yd0:
The structure of Influenza Polymerase Basic Protein 2 (PB2) Bound to An Azaindole- Tetrazole Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Influenza Polymerase Basic Protein 2 (PB2) Bound to An Azaindole- Tetrazole Inhibitor
(pdb code 4yd0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Influenza Polymerase Basic Protein 2 (PB2) Bound to An Azaindole- Tetrazole Inhibitor, PDB code: 4yd0: Fluorine binding site 1 out of 1 in 4yd0Go back to Fluorine Binding Sites List in 4yd0
Fluorine binding site 1 out
of 1 in the Influenza Polymerase Basic Protein 2 (PB2) Bound to An Azaindole- Tetrazole Inhibitor
Mono view Stereo pair view
Reference:
M.J.Boyd,
U.K.Bandarage,
H.Bennett,
R.R.Byrn,
I.Davies,
W.Gu,
M.Jacobs,
M.W.Ledeboer,
B.Ledford,
J.R.Leeman,
E.Perola,
T.Wang,
Y.Bennani,
M.P.Clark,
P.S.Charifson.
Isosteric Replacements of the Carboxylic Acid of Drug Candidate Vx-787: Effect of Charge on Antiviral Potency and Kinase Activity of Azaindole-Based Influenza PB2 Inhibitors. Bioorg.Med.Chem.Lett. V. 25 1990 2015.
Page generated: Thu Aug 1 06:58:16 2024
ISSN: ESSN 1464-3405 PubMed: 25827523 DOI: 10.1016/J.BMCL.2015.03.013 |
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