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Atomistry » Fluorine » PDB 4ymq-4zg9 » 4ze1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4ymq-4zg9 » 4ze1 » |
Fluorine in PDB 4ze1: Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active SiteProtein crystallography data
The structure of Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active Site, PDB code: 4ze1
was solved by
A.Sagatova,
M.V.Keniya,
R.Wilson,
J.D.A.Tyndall,
B.C.Monk,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ze1:
The structure of Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active Site also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active Site
(pdb code 4ze1). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active Site, PDB code: 4ze1: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 4ze1Go back to Fluorine Binding Sites List in 4ze1
Fluorine binding site 1 out
of 2 in the Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active Site
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 4ze1Go back to Fluorine Binding Sites List in 4ze1
Fluorine binding site 2 out
of 2 in the Saccharomyces Cerevisiae CYP51 Y140F Mutant Complexed with Posaconazole in the Active Site
Mono view Stereo pair view
Reference:
A.A.Sagatova,
M.V.Keniya,
R.K.Wilson,
M.Sabherwal,
J.D.Tyndall,
B.C.Monk.
Triazole Resistance Mediated By Mutations of A Conserved Active Site Tyrosine in Fungal Lanosterol 14 Alpha-Demethylase. Sci Rep V. 6 26213 2016.
Page generated: Sun Dec 13 12:16:39 2020
ISSN: ESSN 2045-2322 PubMed: 27188873 DOI: 10.1038/SREP26213 |
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