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Atomistry » Fluorine » PDB 4ymq-4zg9 » 4zg6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4ymq-4zg9 » 4zg6 » |
Fluorine in PDB 4zg6: Structural Basis For Inhibition of Human Autotaxin By Four Novel CompoundsEnzymatic activity of Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds
All present enzymatic activity of Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds:
3.1.4.39; Protein crystallography data
The structure of Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds, PDB code: 4zg6
was solved by
A.J.Stein,
G.Bain,
J.H.Hutchinson,
J.F.Evans,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4zg6:
The structure of Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds
(pdb code 4zg6). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds, PDB code: 4zg6: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 4zg6Go back to![]() ![]()
Fluorine binding site 1 out
of 2 in the Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds
![]() Mono view ![]() Stereo pair view
Fluorine binding site 2 out of 2 in 4zg6Go back to![]() ![]()
Fluorine binding site 2 out
of 2 in the Structural Basis For Inhibition of Human Autotaxin By Four Novel Compounds
![]() Mono view ![]() Stereo pair view
Reference:
A.J.Stein,
G.Bain,
P.Prodanovich,
A.M.Santini,
J.Darlington,
N.M.Stelzer,
R.S.Sidhu,
J.Schaub,
L.Goulet,
D.Lonergan,
I.Calderon,
J.F.Evans,
J.H.Hutchinson.
Structural Basis For Inhibition of Human Autotaxin By Four Potent Compounds with Distinct Modes of Binding. Mol.Pharmacol. V. 88 982 2015.
Page generated: Tue Jul 15 01:54:09 2025
ISSN: ESSN 1521-0111 PubMed: 26371182 DOI: 10.1124/MOL.115.100404 |
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